Connectomic reconstruction of a female Drosophila ventral nerve cord

A Azevedo, E Lesser, JS Phelps, B Mark, L Elabbady… - Nature, 2024 - nature.com
A deep understanding of how the brain controls behaviour requires map** neural circuits
down to the muscles that they control. Here, we apply automated tools to segment neurons …

[HTML][HTML] Circuits for self-motion estimation and walking control in Drosophila

ME Chiappe - Current opinion in neurobiology, 2023 - Elsevier
The brain's evolution and operation are inextricably linked to animal movement, and critical
functions, such as motor control, spatial perception, and navigation, rely on precise …

Ascending neurons convey behavioral state to integrative sensory and action selection brain regions

CL Chen, F Aymanns, R Minegishi, VDV Matsuda… - Nature …, 2023 - nature.com
Knowing one's own behavioral state has long been theorized as critical for contextualizing
dynamic sensory cues and identifying appropriate future behaviors. Ascending neurons …

The processing of proprioceptive signals in distributed networks: insights from insect motor control

C Gebehart, A Büschges - Journal of Experimental Biology, 2024 - journals.biologists.com
The integration of sensory information is required to maintain body posture and to generate
robust yet flexible locomotion through unpredictable environments. To anticipate required …

[HTML][HTML] Biomechanical origins of proprioceptor feature selectivity and topographic maps in the Drosophila leg

A Mamiya, A Sustar, I Siwanowicz, Y Qi, TC Lu… - Neuron, 2023 - cell.com
Our ability to sense and move our bodies relies on proprioceptors, sensory neurons that
detect mechanical forces within the body. Different subtypes of proprioceptors detect …

Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

EC Marin, BJ Morris, T Stürner, AS Champion… - BioRxiv, 2023 - biorxiv.org
Our companion paper introduces the first completely proofread connectome of the nerve
cord of an animal that can walk or fly. The base connectome consists of neuronal …

[PDF][PDF] Tools for comprehensive reconstruction and analysis of Drosophila motor circuits

A Azevedo, E Lesser, B Mark, J Phelps, L Elabbady… - BioRxiv, 2022 - scholar.archive.org
Like the vertebrate spinal cord, the insect ventral nerve cord (VNC) mediates limb sensation
and motor control. Here, we applied automated tools for electron microscopy (EM) volume …

Miniature linear and split-belt treadmills reveal mechanisms of adaptive motor control in walking Drosophila

BG Pratt, SYJ Lee, GM Chou, JC Tuthill - Current Biology, 2024 - cell.com
To navigate complex environments, walking animals must detect and overcome unexpected
perturbations. One technical challenge when investigating adaptive locomotion is …

Organization of an ascending circuit that conveys flight motor state in Drosophila

HSJ Cheong, KN Boone, MM Bennett, F Salman… - Current Biology, 2024 - cell.com
Natural behaviors are a coordinated symphony of motor acts that drive reafferent (self-
induced) sensory activation. Individual sensors cannot disambiguate exafferent (externally …

Flexible circuit mechanisms for context-dependent song sequencing

FA Roemschied, DA Pacheco, MJ Aragon, EC Ireland… - Nature, 2023 - nature.com
Sequenced behaviours, including locomotion, reaching and vocalization, are patterned
differently in different contexts, enabling animals to adjust to their environments. How …