Although the molecular pathways leading to the progressive deterioration of stored red
blood cells (RBC storage lesion) and the clinical relevance of storage‐induced changes …

We review here some recent data about Glucose-6-phosphate dehydrogenase (G6PD), the
housekee** X-linked gene encoding the first enzyme of the pentose phosphate pathway …

Storage of packed red blood cells (RBCs) is associated with progressive accumulation of
lesions, mostly triggered by energy and oxidative stresses, which potentially compromise the …

Although artemisinin-based combination therapies (ACTs) treat Plasmodium falciparum
malaria effectively throughout most of the world, the recent expansion of ACT-resistant …

Glucose-6-phosphate dehydrogenase (G6PD) was one of the first genes found to be
associated with variable drug response. It is also very polymorphic, with G6PD deficiency …

Malaria is still one of the most threatening diseases worldwide. The high drug resistance
rates of malarial parasites make its eradication difficult and furthermore necessitate the …

The asexual intraerythrocytic development of Plasmodium falciparum, causing the most
severe form of human malaria, is marked by extensive host cell remodeling. Throughout the …

Proteomics is improving malaria research by providing global information on relevant
protein sets from the parasite and the host in connection with its cellular structures and …

The malarial parasite Plasmodium falciparum is exposed to substantial redox challenges
during its complex life cycle. In intraerythrocytic parasites, haemoglobin breakdown is a …

As a key enzyme in the pentose phosphate pathway (PPP), glucose-6-phosphate
dehydrogenase (G6PDH) provides nicotinamide adenine dinucleotide phosphate (NADPH) …