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Hyperpolarized 129Xe MRI of the human lung
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
Regional map** of gas uptake by blood and tissue in the human lung using hyperpolarized xenon‐129 MRI
Purpose To develop a breathhold acquisition for regional map** of ventilation and the
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …
Simultaneous magnetic resonance imaging of ventilation distribution and gas uptake in the human lung using hyperpolarized xenon-129
Despite a myriad of technical advances in medical imaging, as well as the growing need to
address the global impact of pulmonary diseases, such as asthma and chronic obstructive …
address the global impact of pulmonary diseases, such as asthma and chronic obstructive …
Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI
Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
Molecular imaging using hyperpolarized 13C
MRI provides unsurpassed soft tissue contrast, but the inherent low sensitivity of this
modality has limited the clinical use to imaging of water protons. With hyperpolarization …
modality has limited the clinical use to imaging of water protons. With hyperpolarization …
Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans
Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
Atlas-driven lung lobe segmentation in volumetric X-ray CT images
High-resolution X-ray computed tomography (CT) imaging is routinely used for clinical
pulmonary applications. Since lung function varies regionally and because pulmonary …
pulmonary applications. Since lung function varies regionally and because pulmonary …
MRI of the lungs using hyperpolarized noble gases
The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased
using optical pum** methods by four to five orders of magnitude. This extraordinary gain …
using optical pum** methods by four to five orders of magnitude. This extraordinary gain …
Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved‐phase MRI
Magnetic‐resonance spectroscopy and imaging using hyperpolarized xenon‐129 show
great potential for evaluation of the most important function of the human lung‐‐gas …
great potential for evaluation of the most important function of the human lung‐‐gas …