[HTML][HTML] Multimodal molecular imaging in drug discovery and development
I Vermeulen, EM Isin, P Barton, B Cillero-Pastor… - Drug discovery today, 2022 - Elsevier
In addition to individual imaging techniques, the combination and integration of several
imaging techniques, so-called multimodal imaging, can provide large amounts of …
imaging techniques, so-called multimodal imaging, can provide large amounts of …
Nanoparticles for super-resolution microscopy: intracellular delivery and molecular targeting
Following an overview of the approaches and techniques used to acheive super-resolution
microscopy, this review presents the advantages supplied by nanoparticle based probes for …
microscopy, this review presents the advantages supplied by nanoparticle based probes for …
Correlative SIP-FISH-Raman-SEM-NanoSIMS links identity, morphology, biochemistry, and physiology of environmental microbes
Microscopic and spectroscopic techniques are commonly applied to study microbial cells but
are typically used on separate samples, resulting in population-level datasets that are …
are typically used on separate samples, resulting in population-level datasets that are …
Characterization and morphological methods for oral biofilm visualization: where are we nowadays?
The oral microbiome represents an essential component of the oral ecosystem whose
symbiotic relationship contributes to health maintenance. The biofilm represents a state of …
symbiotic relationship contributes to health maintenance. The biofilm represents a state of …
Multimodal and multiscale correlative elemental imaging: From whole tissues down to organelles
Chemical elements, especially metals, play very specific roles in the life sciences. The
implementation of correlative imaging methods, of elements on the one hand and of …
implementation of correlative imaging methods, of elements on the one hand and of …
Subcellular protein turnover in human neural progenitor cells revealed by correlative electron microscopy and nanoscale secondary ion mass spectrometry imaging
Protein turnover is a critical process for accurate cellular function, in which damaged
proteins in the cells are gradually replaced with newly synthesized ones. Many previous …
proteins in the cells are gradually replaced with newly synthesized ones. Many previous …
Subcellular ToF-SIMS Imaging of the Snow Alga Sanguina nivaloides by Combining High Mass and High Lateral Resolution Acquisitions
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging has demonstrated great
potential for metabolic imaging; however, achieving sufficiently high lateral and mass …
potential for metabolic imaging; however, achieving sufficiently high lateral and mass …
Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans
BN Conn, JA Lieberman, P Chatman, K Cotton… - Frontiers in …, 2024 - frontiersin.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in>
152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The …
152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The …
Morphological correlates of synaptic protein turnover in the mouse brain
F Li, JN Bahr, FAL Bierth, S Reshetniak… - Life Science …, 2024 - life-science-alliance.org
Synaptic proteins need to be replaced regularly, to maintain function and to prevent
damage. It is unclear whether this process, known as protein turnover, relates to synaptic …
damage. It is unclear whether this process, known as protein turnover, relates to synaptic …
The High Resolutive Detection of TiO2 Nanoparticles in Human Corneocytes via TEM/NanoSIMS Correlation
M Janin, A Delaune, D Gibouin, F Delaroche, B Klaes… - Applied Sciences, 2023 - mdpi.com
Titanium dioxide (TiO2) nanoparticles (NPs) are the subject of numerous studies and
controversies on the risks they could pose to the environment and human health. When in …
controversies on the risks they could pose to the environment and human health. When in …