Light‐sheet fluorescence microscopy (LSFM) introduces fast scanning of biological
phenomena with deep photon penetration and minimal phototoxicity. This advancement …

Aim Coronary artery disease (CAD) is the leading cause of mortality. Though percutaneous
transluminal angioplasty followed by stenting is still the default treatment of choice for …

Revascularization is crucial for treating myocardial infarction (MI). Nitric oxide (NO), at an
appropriate concentration, is recognized as an ideal and potent pro-angiogenic factor …

Background: Collateral arteries act as natural bypasses which reroute blood flow to ischemic
regions and facilitate tissue regeneration. In an injured heart, neonatal artery endothelial …

Cauterization of the root of the left coronary artery (LCA) in the neonatal heart on postnatal
day 1 (P1) resulted in large, reproducible lesions of the left ventricle (LV), and an attendant …

Computational hemodynamic simulations are becoming increasingly important for
cardiovascular research and clinical practice, yet incorporating numerical simulations of …

Revascularization of ischemic myocardium following cardiac damage is an important step in
cardiac regeneration. However, the mechanism of arteriogenesis has not been well …

Mechanical forces are essential for coordinating cardiac morphogenesis, but much remains
to be discovered about the interactions between mechanical forces and the …

The mammalian neonatal heart can regenerate for 1 week after birth, after which, the
majority of cardiomyocytes exit the cell cycle. Recent studies demonstrated that calcineurin …

We present a 3D discrete‐continuum model to simulate blood pressure in large
microvascular tissues in the absence of known capillary network architecture. Our hybrid …