The clustered regularly interspaced short palindromic repeats (CRISPR) renaissance was
catalysed by the discovery that RNA-guided prokaryotic CRISPR-associated (Cas) proteins …

Viruses and their hosts are engaged in a constant arms race leading to the evolution of
antiviral defence mechanisms. Recent studies have revealed that the immune arsenal of …

Abstract Proksee (https://proksee. ca) provides users with a powerful, easy-to-use, and
feature-rich system for assembling, annotating, analysing, and visualizing bacterial …

Bacteria and archaea have developed multiple antiviral mechanisms, and genomic
evidence indicates that several of these antiviral systems co-occur in the same strain. Here …

Background Viral-encoded auxiliary metabolic genes (AMGs) are important toolkits for
modulating their hosts' metabolisms and the microbial-driven biogeochemical cycles …

We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60
cities over 3 years, representing the first systematic, worldwide catalog of the urban …

Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …

CRISPR–Cas interference is mediated by Cas effector nucleases that are either components
of multisubunit complexes—in class 1 CRISPR–Cas systems—or domains of a single …

Bacteriophages are viruses that infect bacteria or archaea. Understanding the diverse and
intricate genomic architectures of phages is essential to study microbial ecosystems and …

Many microbes in nature reside in dense, metabolically interdependent communities. We
investigated the nature and extent of microbe-virus interactions in relation to microbial …