Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors
MZ Khan, L He - Psychopharmacology, 2017 - Springer
Background In the central nervous system (CNS), G protein-coupled receptors (GPCRs) are
the most fruitful targets for neuropsychopharmacological drug development. Rhodopsin …
the most fruitful targets for neuropsychopharmacological drug development. Rhodopsin …
GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer
Y Long, J Guo, J Chen, J Sun, H Wang… - … and Targeted Therapy, 2023 - nature.com
In the treatment of most malignancies, radiotherapy plays a significant role. However, the
resistance of cancer cells to ionizing radiation (IR) is the main reason for the failure of …
resistance of cancer cells to ionizing radiation (IR) is the main reason for the failure of …
[HTML][HTML] GPR162 is a beta cell CART receptor
A Lindqvist, M Abels, L Shcherbina, M Ngara… - Iscience, 2023 - cell.com
Cocaine and amphetamine-regulated transcript (CART) is expressed in pancreatic islet cells
and neuronal elements. We have previously established insulinotropic actions of CART in …
and neuronal elements. We have previously established insulinotropic actions of CART in …
Increased burden of rare protein‐truncating variants in constrained, brain‐specific and synaptic genes in extremely impulsively violent males with antisocial …
D Mušálková, A Přistoupilová… - Genes, brain and …, 2024 - Wiley Online Library
The genetic correlates of extreme impulsive violence are poorly understood, and there have
been few studies that have characterized a large group of affected individuals both clinically …
been few studies that have characterized a large group of affected individuals both clinically …
mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish …
V Caruso, S Sreedharan, VP Carlini, JA Jacobsson… - Gene, 2016 - Elsevier
G protein–coupled receptors (GPCRs) are a class of integral membrane proteins mediating
intercellular interactions of fundamental physiological importance for survival including …
intercellular interactions of fundamental physiological importance for survival including …
[PDF][PDF] IDENTIFICAÇÃO DE GPCRS ENVOLVIDOS NO CONTROLE HIPOTALÂMICO DO BALANÇO ENERGÉTICO
ET CORRESPONDE, ÀVFDAT DEFENDIDA… - repositorio.unicamp.br
Obesidade e sobrepeso afetam mais da metade da população mundial, sendo hoje
considerados problemas de saúde pública. O controle do peso corporal, comportamento …
considerados problemas de saúde pública. O controle do peso corporal, comportamento …