Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement
R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
A comprehensive review of the global efforts on COVID-19 vaccine development
Y Li, R Tenchov, J Smoot, C Liu, S Watkins… - ACS Central …, 2021 - ACS Publications
A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development | ACS
Central Science ACS ACS Publications C&EN CAS Find my institution Log In ACS Central …
Central Science ACS ACS Publications C&EN CAS Find my institution Log In ACS Central …
Lipid nanoparticles in the development of mRNA vaccines for COVID-19
Abstract Coronavirus disease (COVID-19) was first reported in December 2019, Hubei
Province, China. As on 9th December 2021, severe acute respiratory syndrome-coronavirus …
Province, China. As on 9th December 2021, severe acute respiratory syndrome-coronavirus …
Overcoming barriers for siRNA therapeutics: from bench to bedside
The RNA interference (RNAi) pathway possesses immense potential in silencing any gene
in human cells. Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of …
in human cells. Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
Lipid nanoparticle technologies for nucleic acid delivery: A nanoarchitectonics perspective
Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …
Lipid and polymer-based nanoparticle siRNA delivery systems for cancer therapy
RNA interference (RNAi) uses small interfering RNAs (siRNAs) to mediate gene-silencing in
cells and represents an emerging strategy for cancer therapy. Successful RNAi-mediated …
cells and represents an emerging strategy for cancer therapy. Successful RNAi-mediated …
Cationic lipids for gene delivery: Many players, one goal
Lipid-based carriers represent the most widely used alternative to viral vectors for gene
expression and gene silencing purposes. This class of non-viral vectors is particularly …
expression and gene silencing purposes. This class of non-viral vectors is particularly …
A review of mechanistic insight and application of pH-sensitive liposomes in drug delivery
SR Paliwal, R Paliwal, SP Vyas - Drug delivery, 2015 - Taylor & Francis
The pH-sensitive liposomes have been extensively used as an alternative to conventional
liposomes in effective intracellular delivery of therapeutics/antigen/DNA/diagnostics to …
liposomes in effective intracellular delivery of therapeutics/antigen/DNA/diagnostics to …
Strategies in the design of endosomolytic agents for facilitating endosomal escape in nanoparticles
Nanoparticles (NPs) are one of the leading and promising technologies for gene and drug
delivery. However, despite continuous advancements in the delivery of NPs, endosomal …
delivery. However, despite continuous advancements in the delivery of NPs, endosomal …