Mitoribosome biogenesis is a complex process involving RNA elements encoded in the
mitochondrial genome and mitoribosomal proteins typically encoded in the nuclear genome …

The formation of chloroplasts can be traced back to an ancient event in which a eukaryotic
host cell containing mitochondria ingested a cyanobacterium. Since then, chloroplasts have …

The prokaryotic translation elongation factor P (EF-P) and the eukaryotic/archaeal
counterparts eIF5A/aIF5A are proteins that serve a crucial role in mitigating ribosomal …

Mitochondrial gene expression relies on mitoribosomes to translate mitochondrial mRNAs.
The biogenesis of mitoribosomes is an intricate process involving multiple assembly factors …

Mitochondria contain their own genetic information and a dedicated translation system to
express it. The mitochondrial ribosome is assembled from mitochondrial-encoded RNA and …

Neurons in the central nervous system are among the most metabolically active cells in the
body, characterized by high oxygen consumption utilizing glucose both aerobically and …

Ribosomes are large macromolecular complexes composed of both proteins and RNA, that
require a plethora of factors and post-transcriptional modifications for their biogenesis. In …

Non-coding RNAs (ncRNAs) are a heterogeneous group, in terms of structure and sequence
length, consisting of RNA molecules that do not code for proteins. These ncRNAs have a …

Mitochondria rely on coordinated expression of their own mitochondrial DNA (mtDNA) with
that of the nuclear genome for their biogenesis. The bacterial ancestry of mitochondria has …

Import and assembly of mitochondrial proteins into multimeric complexes are essential for
cellular function. Yet, many steps of these processes and the proteins involved remain …