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Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's disease
Despite widespread sex differences in prevalence and presentation of numerous illnesses
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …
Beyond sex differences: short-and long-term effects of pregnancy on the brain
Growing attention has been directed to the inclusion of females in neuroscience studies, and
to the importance of studying sex as a biological variable. However, how female-specific …
to the importance of studying sex as a biological variable. However, how female-specific …
Neuroanatomical changes observed over the course of a human pregnancy
Pregnancy is a period of profound hormonal and physiological changes experienced by
millions of women annually, yet the neural changes unfolding in the maternal brain …
millions of women annually, yet the neural changes unfolding in the maternal brain …
Solving neurodegeneration: common mechanisms and strategies for new treatments
Across neurodegenerative diseases, common mechanisms may reveal novel therapeutic
targets based on neuronal protection, repair, or regeneration, independent of etiology or site …
targets based on neuronal protection, repair, or regeneration, independent of etiology or site …
Ovarian steroid hormones: A long overlooked but critical contributor to brain aging and Alzheimer's disease
S Jett, E Schelbaum, G Jang… - Frontiers in aging …, 2022 - frontiersin.org
Ovarian hormones, particularly 17β-estradiol, are involved in numerous neurophysiological
and neurochemical processes, including those subserving cognitive function. Estradiol plays …
and neurochemical processes, including those subserving cognitive function. Estradiol plays …
[HTML][HTML] Role of glial cells in the generation of sex differences in neurodegenerative diseases and brain aging
JA Chowen, LM Garcia-Segura - Mechanisms of Ageing and Development, 2021 - Elsevier
Diseases and aging-associated alterations of the nervous system often show sex-specific
characteristics. Glial cells play a major role in the endogenous homeostatic response of …
characteristics. Glial cells play a major role in the endogenous homeostatic response of …
[HTML][HTML] The interplay of oxytocin and sex hormones
The neuropeptide oxytocin has historically been associated with reproduction and maternal
behavior. However, more recent research has uncovered that oxytocin has a much wider …
behavior. However, more recent research has uncovered that oxytocin has a much wider …
The maternal brain: Region‐specific patterns of brain aging are traceable decades after childbirth
Pregnancy involves maternal brain adaptations, but little is known about how parity
influences women's brain aging trajectories later in life. In this study, we replicated previous …
influences women's brain aging trajectories later in life. In this study, we replicated previous …
Characterizing the brain structural adaptations across the motherhood transition
Women that become mothers face notable physiological adaptations during this life-period.
Neuroimaging studies of the last decade have provided grounded evidence that women's …
Neuroimaging studies of the last decade have provided grounded evidence that women's …
Enhancing brain health in the global south through a sex and gender lens
Gender inequality substantially impacts society, disproportionately disadvantaging women,
especially in the global south. This inequality correlates with brain health outcomes for …
especially in the global south. This inequality correlates with brain health outcomes for …