Role of matrix metalloproteinases in angiogenesis and cancer

S Quintero-Fabián, R Arreola… - Frontiers in …, 2019 - frontiersin.org
During angiogenesis, new vessels emerge from existing endothelial lined vessels to
promote the degradation of the vascular basement membrane and remodel the extracellular …

The role of integrins in inflammation and angiogenesis

OJ Mezu-Ndubuisi, A Maheshwari - Pediatric research, 2021 - nature.com
Integrins are heterodimeric transmembrane cell adhesion molecules made up of alpha (α)
and beta (β) subunits arranged in numerous dimeric pairings. These complexes have …

An overview of drug delivery systems

KK Jain - Drug delivery systems, 2020 - Springer
This is an overview of the current drug delivery systems (DDSs) starting with various routes
of drug administration. Various drug formulations are then described as well as devices …

Nanotechnology for angiogenesis: opportunities and challenges

S Kargozar, F Baino, S Hamzehlou… - Chemical Society …, 2020 - pubs.rsc.org
Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Peptide-based drug delivery systems

D Berillo, A Yeskendir, Z Zharkinbekov, K Raziyeva… - Medicina, 2021 - mdpi.com
Peptide-based drug delivery systems have many advantages when compared to synthetic
systems in that they have better biocompatibility, biochemical and biophysical properties …

Microfluidics technology for the design and formulation of nanomedicines

E Jaradat, E Weaver, A Meziane, DA Lamprou - Nanomaterials, 2021 - mdpi.com
In conventional drug administration, drug molecules cross multiple biological barriers,
distribute randomly in the tissues, and can release insufficient concentrations at the desired …

Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications

I Jarak, CL Varela, ET da Silva, FFM Roleira… - European Journal of …, 2020 - Elsevier
Pluronics are a class of amphiphilic tri-block copolymers with wide pharmaceutical
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …

[HTML][HTML] Integrin-targeting peptides for the design of functional cell-responsive biomaterials

J Zhao, F Santino, D Giacomini, L Gentilucci - Biomedicines, 2020 - mdpi.com
Integrins are a family of cell surface receptors crucial to fundamental cellular functions such
as adhesion, signaling, and viability, deeply involved in a variety of diseases, including the …

Improving nanotherapy delivery and action through image-guided systems pharmacology

TSC Ng, MA Garlin, R Weissleder, MA Miller - Theranostics, 2020 - pmc.ncbi.nlm.nih.gov
Despite recent advances in the translation of therapeutic nanoparticles (TNPs) into the clinic,
the field continues to face challenges in predictably and selectively delivering nanomaterials …

Charge‐conversion strategies for nucleic acid delivery

K Dutta, R Das, J Medeiros, P Kanjilal… - Advanced functional …, 2021 - Wiley Online Library
Nucleic acids are considered as one of the most potent therapeutic modalities, as their roles
go beyond storing genetic information and chemical energy or as signal transducers …