NMR spectroscopy as a characterization tool enabling biologics formulation development
J Ma, C Pathirana, DQ Liu, SA Miller - Journal of Pharmaceutical and …, 2023 - Elsevier
This review highlights recent advancements in using high resolution nuclear magnetic
resonance (NMR) spectroscopy as a characterization tool to expedite biologics formulation …
resonance (NMR) spectroscopy as a characterization tool to expedite biologics formulation …
USFDA-approved parenteral peptide formulations and excipients: Industrial perspective
Parenteral preparations are sterile and non-pyrogenic formulations designed for delivery
into the human or animal body by injection, infusion, or implantation. Peptides are widely …
into the human or animal body by injection, infusion, or implantation. Peptides are widely …
Molecular Investigation of SNAC as an Oral Peptide Permeation Enhancer in Lipid Membranes via Solid-State NMR
Oral peptide therapeutics are increasingly favored in the pharmaceutical industry for their
ease of use and better patient adherence. However, they face challenges with poor oral …
ease of use and better patient adherence. However, they face challenges with poor oral …
Industrial Horizons in Pharmaceutical Science
The mission of industrial science in the pharmaceutical sector is to drive innovation in drug
development, delivery, and manufacturing, to fulfill unmet medical needs, and to provide …
development, delivery, and manufacturing, to fulfill unmet medical needs, and to provide …
In-situ biophysical characterization of high-concentration protein formulations using wNMR
High-concentration protein formulation is of paramount importance in patient-centric drug
product development, but it also presents challenges due to the potential for enhanced …
product development, but it also presents challenges due to the potential for enhanced …
[HTML][HTML] Interaction of preservatives with contact materials during filling and storage of parenteral liquid formulations
P Gottschalk, P Schlossbauer, L Schleicher… - European Journal of …, 2025 - Elsevier
Silicone tubing is a frequently used material in pharmaceutical filling processes for
parenteral formulations, as its characteristics like flexibility, chemical resistance and easy …
parenteral formulations, as its characteristics like flexibility, chemical resistance and easy …
Study on the evaluation method of cigarette astringency in the simulated oral environment
Cigarettes with pronounced astringency can diminish consumers' enjoyment. However, due
to the complex composition of cigarettes, quantifying astringency intensity accurately has …
to the complex composition of cigarettes, quantifying astringency intensity accurately has …
Best Practices for Submission of NMR Data to Support Higher Order Structure Assessment of Generic Peptide Drugs
K Chen, CJ Smith - The AAPS Journal, 2023 - Springer
Peptides are a growing class of therapeutics (1, 2) and defined by the US Food and Drug
Administration (FDA) as a polymer composed of 40 or fewer amino acid residues regardless …
Administration (FDA) as a polymer composed of 40 or fewer amino acid residues regardless …
Advances in NMR spectroscopy of small molecules in solution
P Nolis - 2023 - books.rsc.org
This book chapter covers relevant articles published in peer-reviewed journals in 2022 in
the field of NMR spectroscopy of small molecules in solution. Articles that appeared in 2022 …
the field of NMR spectroscopy of small molecules in solution. Articles that appeared in 2022 …
Nuclear spin relaxation
J Kowalewski - 2020 - books.rsc.org
The review covers the progress in the field of NMR relaxation in fluids primarily during 2019.
Since the topic is returning to this volume SPR after a break of a few years, some highlights …
Since the topic is returning to this volume SPR after a break of a few years, some highlights …