Psychosis biotypes: replication and validation from the B-SNIP consortium

BA Clementz, DA Parker, RL Trotti… - Schizophrenia …, 2022 - academic.oup.com
Current clinical phenomenological diagnosis in psychiatry neither captures biologically
homologous disease entities nor allows for individualized treatment prescriptions based on …

The interplay between diabetes and alzheimer's disease—In the hunt for biomarkers

A Kubis-Kubiak, A Dyba, A Piwowar - International Journal of Molecular …, 2020 - mdpi.com
The brain is an organ in which energy metabolism occurs most intensively and glucose is an
essential and dominant energy substrate. There have been many studies in recent years …

[HTML][HTML] Association between pectus excavatum and congenital genetic disorders: A systematic review and practical guide for the treating physician

RJ Billar, W Manoubi, SG Kant, RMH Wijnen… - Journal of pediatric …, 2021 - Elsevier
Background Pectus excavatum (PE) could be part of a genetic disorder, which then has
implications regarding comorbidity, the surgical correction of PE, and reproductive choices …

Discovering comorbid diseases using an inter-disease interactivity network based on biobank-scale PheWAS data

Y Nam, SH Jung, JS Yun, V Sriram, P Singhal… - …, 2023 - academic.oup.com
Motivation Understanding comorbidity is essential for disease prevention, treatment and
prognosis. In particular, insight into which pairs of diseases are likely or unlikely to co-occur …

Analysis of disease comorbidity patterns in a large-scale China population

M Guo, Y Yu, T Wen, X Zhang, B Liu, J Zhang… - BMC medical …, 2019 - Springer
Background Disease comorbidity is popular and has significant indications for disease
progress and management. We aim to detect the general disease comorbidity patterns in …

Protein–protein interaction network analysis reveals several diseases highly associated with polycystic ovarian syndrome

B Ramly, N Afiqah-Aleng… - International journal of …, 2019 - mdpi.com
Based on clinical observations, women with polycystic ovarian syndrome (PCOS) are prone
to develo** several other diseases, such as metabolic and cardiovascular diseases …

Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects

O Zolotareva, OV Saik, C Königs, EY Bragina… - Scientific reports, 2019 - nature.com
Asthma and hypertension are complex diseases coinciding more frequently than expected
by chance. Unraveling the mechanisms of comorbidity of asthma and hypertension is …

GUILDify v2. 0: A tool to identify molecular networks underlying human diseases, their comorbidities and their druggable targets

J Aguirre-Plans, J Piñero, F Sanz, LI Furlong… - Journal of molecular …, 2019 - Elsevier
The genetic basis of complex diseases involves alterations on multiple genes. Unraveling
the interplay between these genetic factors is key to the discovery of new biomarkers and …

The shared genetic architecture between epidemiological and behavioral traits with lung cancer

RW Pettit, J Byun, Y Han, QT Ostrom, J Edelson… - Scientific reports, 2021 - nature.com
The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to
identify novel phenotypes associated with lung cancer using cross-trait linkage …

PCOSKBR2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome

M Sharma, RS Barai, I Kundu, S Bhaye, K Pokar… - Scientific reports, 2020 - nature.com
Abstract PolyCystic Ovary Syndrome KnowledgeBase (PCOSKBR2) is a manually curated
database with information on 533 genes, 145 SNPs, 29 miRNAs, 1,150 pathways, and 1,237 …