Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Purpose Gut microbiota regulate intestinal function and health. However, mounting evidence
indicates that they can also influence the immune and nervous systems and vice versa. This …

Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving …

Mast Cells, Mastocytosis, and Related Disorders | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

The ability of the nervous system to sense environmental stimuli and to relay these signals to
immune cells via neurotransmitters and neuropeptides is indispensable for effective …

Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …

The discovery of corticotropin-releasing factor (CRF) or CRH defining the upper regulatory
arm of the hypothalamic-pituitary-adrenal (HPA) axis, along with the identification of the …

The intricate relationship between stress and skin conditions has been documented since
ancient times. Recent clinical observations also link psychological stress to the onset or …

Autism spectrum disorders (ASDs) affect as many as 1 in 45 children and are characterized
by deficits in sociability and communication, as well as stereotypic movements. Many …