Advances over the past few years have begun to enable prediction and design of
macromolecular structures at near-atomic accuracy. Progress has stemmed from the …

Recent advances in single molecule experiments have raised many challenges. These
challenges can be met by a proper understanding of the inter-and intra-molecular …

The coiled coil is arguably the simplest protein-structure motif and probably the most
ubiquitous facilitator of protein-protein interactions. Coiled coils comprise two or more α …

Until now it has been impractical to observe protein folding in silico for proteins larger than
50 residues. Limitations of both force field accuracy and computational efficiency make the …

Unfolding of proteins by forced stretching with atomic force microscopy or laser tweezer
experiments complements more classical techniques using chemical denaturants or …

The use of simple theoretical models has provided a considerable contribution to our
present understanding of the means by which proteins adopt their native fold from the …

Ligand binding to recombinant bovine acyl-CoA binding protein (ACBP) was examined
using isothermal microcalorimetry. Microcalorimetric measurements confirm that the binding …

The acyl-coenzyme A-binding proteins (ACBPs) contain 26 highly conserved sequence
positions. The majority of these have been mutated in the bovine protein, and their influence …

In plants, lipid trafficking within and inside the cell is carried out by lipid-binding and transfer
proteins. Ligands for these proteins are building and signaling lipid molecules, secondary …

Abstract Cytosolic 10-kDa acyl-CoA-binding proteins (ACBPs) function in the storage and
intracellular transport of acyl-CoA esters in eukaryotes. Fatty acids synthesized de novo in …