Primary lateral sclerosis (PLS) has been traditionally viewed as a distinct upper motor
neuron condition (UMN) but is increasingly regarded as a sub-phenotype within the …

The cerebellum is crucial for both motor and nonmotor functions. Alzheimer's disease (AD),
alongside other dementias such as vascular dementia (VaD), Lewy body dementia (DLB) …

Brain functional connectivity (FC) extracted from resting‐state fMRI (RS‐fMRI) has become a
popular approach for diagnosing various neurodegenerative diseases, including …

Abstract See Lancaster and Hall (doi: 10.1093/awv330) for a scientific commentary on this
article. Schizophrenia is increasingly recognized as a neurodevelopmental disorder with …

Background Primary lateral sclerosis is a progressive upper-motor-neuron disorder
associated with markedly longer survival than ALS. In contrast to ALS, the genetic …

Advances in neuroimaging, complementing histopathological insights, have established a
multi-system involvement of cerebral networks beyond the traditional neuromuscular …

Primary lateral sclerosis (PLS) is characterized by insidious onset of progressive upper
motor neuron dysfunction in the absence of clinical signs of lower motor neuron …

Emerging studies corroborate the importance of neuroimaging biomarkers and machine
learning to improve diagnostic classification of amyotrophic lateral sclerosis (ALS). While …

Amyotrophic lateral sclerosis is a relentlessly progressive multi-system condition. The
clinical picture is dominated by upper and lower motor neuron degeneration, but extra-motor …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …