The monovalent methyl group is derived from methane through the removal of a hydrogen
atom, 1 and its etymology is directly related to the discovery of methanol. 2 The first reports …

Pollution from pharmaceuticals in the aquatic environment is now recognized as an
environmental concern in many countries. This has led to the creation of an extensive area …

Antimicrobial resistance seriously threatened human health, and new antimicrobial agents
are desperately needed. As one of the largest classes of plant secondary metabolite …

This review aims to highlight the applications of one of the most prominent optical biosensor
technologies, surface plasmon resonance (SPR), in the drug discovery process and quality …

In this review, we consider the two prevailing hypotheses for the mechanisms that control the
bioaccumulation of perfluorinated alkyl acids (PFAAs). The first assumes that partitioning to …

In this review, we first summarize the structure and properties of biological membranes and
the routes of passive drug transfer through physiological barriers. Lipophilicity is then …

Most clinical antibiotics do not have efficacy against Gram‐negative pathogens, mainly
because these cells are protected by the permeability barrier comprising the two …

We report an atomistic physical model for the passive membrane permeability of cyclic
peptides. The computational modeling was performed in advance of the experiments and …

It is generally thought that many drug molecules are transported across biological
membranes via passive diffusion at a rate related to their lipophilicity. However, the types of …

The usefulness of Caco‐2 cell monolayers in determining the intestinal drug absorption of
potential drug candidates as such and from delivery systems, elucidating the underlying …