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Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …
chemicals of potential concern to human health and the environment. Based on information …
Immunotoxic effects of environmental pollutants in marine mammals
Due to their marine ecology and life-history, marine mammals accumulate some of the
highest levels of environmental contaminants of all wildlife. Given the increasing prevalence …
highest levels of environmental contaminants of all wildlife. Given the increasing prevalence …
Effect-directed analysis supporting monitoring of aquatic environments—an in-depth overview
Aquatic environments are often contaminated with complex mixtures of chemicals that may
pose a risk to ecosystems and human health. This contamination cannot be addressed with …
pose a risk to ecosystems and human health. This contamination cannot be addressed with …
[HTML][HTML] IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
X Chang, YM Tan, DG Allen, S Bell, PC Brown… - Toxics, 2022 - mdpi.com
During the past few decades, the science of toxicology has been undergoing a
transformation from observational to predictive science. New approach methodologies …
transformation from observational to predictive science. New approach methodologies …
In vitro to in vivo extrapolation for high throughput prioritization and decision making
In vitro chemical safety testing methods offer the potential for efficient and economical tools
to provide relevant assessments of human health risk. To realize this potential, methods are …
to provide relevant assessments of human health risk. To realize this potential, methods are …
Environmental chemistry of organosiloxanes
C Rücker, K Kümmerer - Chemical Reviews, 2015 - ACS Publications
Although around us for more than six decades, siloxanes are considered emerging
environmental contaminants. 1− 5 Emerging here means that previously they were not …
environmental contaminants. 1− 5 Emerging here means that previously they were not …
[HTML][HTML] Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models
Nominal effect concentrations from in vitro toxicity assays may lead to inaccurate estimations
of in vivo toxic doses because the nominal concentration poorly reflects the concentration at …
of in vivo toxic doses because the nominal concentration poorly reflects the concentration at …
Quantitative adverse outcome pathways and their application to predictive toxicology
A quantitative adverse outcome pathway (qAOP) consists of one or more biologically based,
computational models describing key event relationships linking a molecular initiating event …
computational models describing key event relationships linking a molecular initiating event …
A next-generation risk assessment case study for coumarin in cosmetic products
MT Baltazar, S Cable, PL Carmichael… - Toxicological …, 2020 - academic.oup.com
Abstract Next-Generation Risk Assessment is defined as an exposure-led, hypothesis-driven
risk assessment approach that integrates new approach methodologies (NAMs) to assure …
risk assessment approach that integrates new approach methodologies (NAMs) to assure …
[ΒΙΒΛΙΟ][B] Bioanalytical tools in water quality assessment
The first edition of Bioanalytical Tools in Water Quality Assessment was released in 2012.
The field has exploded since and the second edition updates and reviews the application of …
The field has exploded since and the second edition updates and reviews the application of …