Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation
and destruction. There is currently no cure for rheumatoid arthritis, and the effectiveness of …

Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …

The central nervous system is lined by meninges, classically known as dura, arachnoid, and
pia mater. We show the existence of a fourth meningeal layer that compartmentalizes the …

Background: Cellular diversity of the lung endothelium has not been systematically
characterized in humans. We provide a reference atlas of human lung endothelial cells …

Patients with bladder cancer (BCa) with clinical lymph node (LN) metastasis have an
extremely poor prognosis. VEGF-C has been demonstrated to play vital roles in LN …

The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

Lymphatic vessels maintain tissue fluid homeostasis by returning to blood circulation
interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …

In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet strip** automated endothelial …