Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

The evolution, assembly, and dynamics of marine holobionts

RA González-Pech, VY Li, V Garcia… - Annual Review of …, 2024 - annualreviews.org
The holobiont concept (ie, multiple living beings in close symbiosis with one another and
functioning as a unit) is revolutionizing our understanding of biology, especially in marine …

Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR

RD Olson, R Assaf, T Brettin, N Conrad… - Nucleic acids …, 2023 - academic.oup.com
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …

Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei

K Billington, C Halliday, R Madden, P Dyer… - Nature …, 2023 - nature.com
Trypanosoma brucei is a model trypanosomatid, an important group of human, animal and
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …

Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell

A Guérin, KM Strelau, K Barylyuk, BA Wallbank… - Cell host & …, 2023 - cell.com
Cryptosporidium is a leading cause of diarrheal disease in children and an important
contributor to early childhood mortality. The parasite invades and extensively remodels …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Babesia duncani multi-omics identifies virulence factors and drug targets

P Singh, S Lonardi, Q Liang, P Vydyam… - Nature …, 2023 - nature.com
Babesiosis is a malaria-like disease in humans and animals that is caused by Babesia
species, which are tick-transmitted apicomplexan pathogens. Babesia duncani causes …

High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription

S Butterworth, K Kordova, S Chandrasekaran… - Cell host & …, 2023 - cell.com
Intracellular pathogens and other endosymbionts reprogram host cell transcription to
suppress immune responses and recalibrate biosynthetic pathways. This reprogramming is …

[HTML][HTML] Host genetics highlights IFN-γ-dependent Toxoplasma genes encoding secreted and non-secreted virulence factors in in vivo CRISPR screens

Y Tachibana, E Hashizaki, M Sasai, M Yamamoto - Cell Reports, 2023 - cell.com
Secreted virulence factors of Toxoplasma to survive in immune-competent hosts have been
extensively explored by classical genetics and in vivo CRISPR screen methods, whereas …

Intrinsic factors driving mosquito vector competence and viral evolution: a review

J Lewis, EN Gallichotte, J Randall, A Glass… - Frontiers in Cellular …, 2023 - frontiersin.org
Mosquitoes are responsible for the transmission of numerous viruses of global health
significance. The term “vector competence” describes the intrinsic ability of an arthropod …