Isatin and its derivatives: a survey of recent syntheses, reactions, and applications
R Kakkar - MedChemComm, 2019 - pubs.rsc.org
Isatin (1H-indole-2, 3-dione) and its derivatives represent an important class of heterocyclic
compounds that can be used as precursors for drug synthesis. Since its discovery, a lot of …
compounds that can be used as precursors for drug synthesis. Since its discovery, a lot of …
The applications of dimethyl sulfoxide as reagent in organic synthesis
XF Wu, K Natte - Advanced Synthesis & Catalysis, 2016 - Wiley Online Library
Dimethyl sulfoxide (DMSO) is one of the most commonly applied organic solvents in
chemical transformations and is utilized widely in industrial processes as well. During the …
chemical transformations and is utilized widely in industrial processes as well. During the …
Metal‐free cross‐dehydrogenative coupling (CDC): molecular iodine as a versatile catalyst/reagent for CDC reactions
The development of ecofriendly methods for carbon–carbon (C− C) and carbon–heteroatom
(C− Het) bond formation is of great significance in modern‐day research. Metal‐free cross …
(C− Het) bond formation is of great significance in modern‐day research. Metal‐free cross …
Electrohalogenation of organic compounds
MR Scheide, CR Nicoleti, GM Martins… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Herein, we present an overview of recent advances in the electrochemical halogenation of
organic compounds. Halogen-containing compounds are essential building blocks for post …
organic compounds. Halogen-containing compounds are essential building blocks for post …
AC= O⋅⋅⋅ Isothiouronium Interaction Dictates Enantiodiscrimination in Acylative Kinetic Resolutions of Tertiary Heterocyclic Alcohols
MD Greenhalgh, SM Smith, DM Walden… - Angewandte …, 2018 - Wiley Online Library
A combination of experimental and computational studies have identified a C= O⋅⋅⋅
isothiouronium interaction as key to efficient enantiodiscrimination in the kinetic resolution of …
isothiouronium interaction as key to efficient enantiodiscrimination in the kinetic resolution of …
Electrocatalytic C–H/N–H coupling of 2′-aminoacetophenones for the synthesis of isatins
P Qian, JH Su, Y Wang, M Bi, Z Zha… - The Journal of Organic …, 2017 - ACS Publications
2′-Aminoacetophenones undergo a C (sp3)–H oxidation followed by intramolecular C–N
bond formation by virtue of a simple electrochemical oxidation in the presence of n-Bu4NI …
bond formation by virtue of a simple electrochemical oxidation in the presence of n-Bu4NI …
Iodine/DMSO oxidations: a contemporary paradigm in C–N bond chemistry
A new era in the organic synthetic world is demanding greener protocols for the execution of
reactions. As the world is progressing towards fewer natural resources and high energy …
reactions. As the world is progressing towards fewer natural resources and high energy …
I2‐Catalyzed Cycloisomerization of Ynamides: Chemoselective and Divergent Access to Indole Derivatives
BH Zhu, SB Ye, ML Nie, ZY **e, YB Wang… - Angewandte …, 2023 - Wiley Online Library
Herein, an I2‐catalyzed unprecedented cycloisomerization of ynamides is developed,
furnishing various functionalized bis (indole) derivatives in generally good to excellent yields …
furnishing various functionalized bis (indole) derivatives in generally good to excellent yields …
Synthesis of Luminescent Indolo[2,1-b]quinazolin-6(12H)-ones via a Sequential Ugi/Iodine-Promoted Cyclization/Staudinger/Aza-Wittig Reaction
ML Yang, L Zhao, HR Chen… - The Journal of Organic …, 2023 - ACS Publications
A new efficient synthesis of indolo [2, 1-b] quinazolin-6 (12 H)-ones via a sequential
Ugi/iodine-promoted cyclization/Staudinger/aza-Wittig reaction was developed. The acid …
Ugi/iodine-promoted cyclization/Staudinger/aza-Wittig reaction was developed. The acid …
K 2 S 2 O 8-mediated metal-free direct C–H functionalization of quinones using arylboronic acids
Direct C–H functionalization of quinones with arylboronic acids is achieved using K2S2O8
as the sole and efficient green catalytic system. This method provides a straightforward and …
as the sole and efficient green catalytic system. This method provides a straightforward and …