Mechanobiology of collective cell behaviours

B Ladoux, RM Mège - Nature reviews Molecular cell biology, 2017 - nature.com
The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Cell–cell junctions organize structural and signaling networks

MA Garcia, WJ Nelson… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Cell–cell junctions link cells to each other in tissues, and regulate tissue homeostasis in
critical cell processes that include tissue barrier function, cell proliferation, and migration …

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

Y Takai, J Miyoshi, W Ikeda, H Ogita - Nature reviews Molecular cell …, 2008 - nature.com
Nectins and nectin-like molecules (Necls) are immunoglobulin-like transmembrane cell
adhesion molecules that are expressed in various cell types. Homophilic and heterophilic …

Nectin and afadin: novel organizers of intercellular junctions

Y Takai, H Nakanishi - Journal of cell science, 2003 - journals.biologists.com
The cadherin superfamily plays key roles in intercellular adhesion. An emerging intercellular
adhesion system, consisting of nectin and afadin, also has roles in organization of a variety …

Adhesion-based self-organization in tissue patterning

TYC Tsai, RM Garner… - Annual review of cell and …, 2022 - annualreviews.org
Since the proposal of the differential adhesion hypothesis, scientists have been fascinated
by how cell adhesion mediates cellular self-organization to form spatial patterns during …

Nectins and nectin‐like molecules: roles in cell adhesion, migration, and polarization

Y Takai, K Irie, K Shimizu, T Sakisaka… - Cancer science, 2003 - Wiley Online Library
Nectins are a family of Ca2+‐independent immunoglobulin‐like cell‐cell adhesion
molecules consisting of four members, which homophilically and heterophilically trans …

Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor

T DeVries-Seimon, Y Li, PM Yao, E Stone… - The Journal of cell …, 2005 - rupress.org
Macrophage death in advanced atherosclerosis promotes necrosis and plaque
destabilization. A likely cause of macrophage death is accumulation of free cholesterol (FC) …

The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

JK Sawyer, NJ Harris, KC Slep, U Gaul… - Journal of Cell Biology, 2009 - rupress.org
Cadherin-based adherens junctions (AJs) mediate cell adhesion and regulate cell shape
change. The nectin–afadin complex also localizes to AJs and links to the cytoskeleton …

Molecular perspective on tight-junction assembly and epithelial polarity

J Miyoshi, Y Takai - Advanced drug delivery reviews, 2005 - Elsevier
Apical–basal polarity and a highly organized actin cytoskeleton are main characteristics of
epithelial cells that support exchange of ions and nutrients from one body compartment to …

Nectins and nectin-like molecules in development and disease

K Mandai, Y Rikitake, M Mori, Y Takai - Current topics in developmental …, 2015 - Elsevier
Nectins and nectin-like molecules (Necls)/Cadms are Ca 2+-independent immunoglobulin
superfamily cell adhesion molecules, expressed in most cell types. Nectins mediate not only …