A review of the global epidemiology of scrub typhus

G Xu, DH Walker, D Jupiter, PC Melby… - PLoS neglected tropical …, 2017 - journals.plos.org
Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one
billion people globally, and causes illness in one million people each year. Caused by …

Scrub typhus ecology: a systematic review of Orientia in vectors and hosts

I Elliott, I Pearson, P Dahal, NV Thomas, T Roberts… - Parasites & vectors, 2019 - Springer
Scrub typhus, caused by Orientia tsutsugamushi, is an important and neglected vector-borne
zoonotic disease with an expanding known distribution. The ecology of the disease is …

A Review of Scrub Typhus (Orientia tsutsugamushi and Related Organisms): Then, Now, and Tomorrow

A Luce-Fedrow, ML Lehman, DJ Kelly… - Tropical medicine and …, 2018 - mdpi.com
Scrub typhus and the rickettsial diseases represent some of the oldest recognized vector-
transmitted diseases, fraught with a rich historical aspect, particularly as applied to …

Engineering of obligate intracellular bacteria: progress, challenges and paradigms

EE McClure, ASO Chávez, DK Shaw… - Nature Reviews …, 2017 - nature.com
It is estimated that approximately one billion people are at risk of infection with obligate
intracellular bacteria, but little is known about the underlying mechanisms that govern their …

[HTML][HTML] Molecular description of a novel Orientia species causing scrub typhus in Chile

K Abarca, C Martínez-Valdebenito… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Scrub typhus is a potentially fatal rickettsiosis caused by Orientia species intracellular
bacteria of the genus Orientia. Although considered to be restricted to the Asia Pacific …

Diagnosis of scrub typhus: recent advancements and challenges

D Kala, S Gupta, R Nagraik, V Verma, A Thakur… - 3 Biotech, 2020 - Springer
Scrub typhus is a mite-borne, acute febrile illness caused by the bacterium Orientia
tsutsugamushi. It is a re-emerging infectious disease of the tsutsugamushi triangle. Scrub …

Scrub typhus: no longer restricted to the tsutsugamushi triangle

J Jiang, AL Richards - Tropical medicine and infectious disease, 2018 - mdpi.com
Scrub typhus is the most important rickettsial disease in the world. Its previous endemic
region was considered to be in Asia, Australia and islands in the Indian and Pacific Oceans; …

[HTML][HTML] Epidemiology of acute febrile illness in Latin America

J Moreira, CS Bressan, P Brasil, AM Siqueira - Clinical Microbiology and …, 2018 - Elsevier
Background The causes of acute febrile illness (AFI) in Latin America are diverse and their
complexity increases as the proportion of fever due to malaria decreases, as malaria control …

Intravenous doxycycline, azithromycin, or both for severe scrub typhus

GM Varghese, D Dayanand… - … England Journal of …, 2023 - Mass Medical Soc
Background The appropriate antibiotic treatment for severe scrub typhus, a neglected but
widespread reemerging zoonotic infection, is unclear. Methods In this multicenter, double …

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species

AL Richards, J Jiang - Tropical medicine and infectious disease, 2020 - mdpi.com
Scrub typhus and its etiological agents, Orientia species, have been around for a very long
time. Historical reference to the rickettsial disease scrub typhus was first described in China …