Oxidative stress and low-grade inflammation in polycystic ovary syndrome: controversies and new insights

A Mancini, C Bruno, E Vergani, C d'Abate… - International Journal of …, 2021 - mdpi.com
The pathophysiology of Polycystic Ovary Syndrome (PCOS) is quite complex and different
mechanisms could contribute to hyperandrogenism and anovulation, which are the main …

[HTML][HTML] Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis

HF Escobar-Morreale, M Luque-Ramírez, F González - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To perform a review and metaanalysis of the studies evaluating the status of
serum inflammatory markers in women with polycystic ovary syndrome (PCOS). DESIGN …

Complications and challenges associated with polycystic ovary syndrome: current perspectives

S Palomba, S Santagni, A Falbo… - International journal of …, 2015 - Taylor & Francis
Polycystic ovary syndrome (PCOS) represents the most common endocrine dysfunction in
fertile women and it is considered a heterogeneous and multifaceted disorder, with multiple …

The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome

HF Escobar-Morreale, M Luque-Ramírez… - Endocrine …, 2005 - academic.oup.com
The genetic mechanisms underlying functional hyperandrogenism and the polycystic ovary
syndrome (PCOS) remain largely unknown. Given the large number of genetic variants …

Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome

KA Toulis, DG Goulis, G Mintziori… - Human reproduction …, 2011 - academic.oup.com
BACKGROUND The relation between polycystic ovary syndrome (PCOS) and
cardiovascular disease (CVD) remains unclear. In an attempt to provide high-quality …

The human obesity gene map: the 2004 update

L Pérusse, T Rankinen, A Zuberi, YC Chagnon… - Obesity …, 2005 - Wiley Online Library
This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …

Comparison of single and combined treatment with exenatide and metformin on menstrual cyclicity in overweight women with polycystic ovary syndrome

K Elkind-Hirsch, O Marrioneaux… - The Journal of …, 2008 - academic.oup.com
Context: Insulin resistance and obesity are common features of the polycystic ovary
syndrome (PCOS). Weight loss and use of insulin-lowering drugs have been shown to …

Indices of low-grade chronic inflammation in polycystic ovary syndrome and the beneficial effect of metformin

E Diamanti-Kandarakis, T Paterakis… - Human …, 2006 - academic.oup.com
BACKGROUND: Women with polycystic ovary syndrome (PCOS) have an increased
prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of cellular …

Central fat excess in polycystic ovary syndrome: relation to low-grade inflammation and insulin resistance

JJ Puder, S Varga, M Kraenzlin… - The Journal of …, 2005 - academic.oup.com
Background: It is controversial whether the polycystic ovary syndrome (PCOS) per se
increases low-grade chronic inflammation and whether this relates to central fat excess. In …

Obesity and polycystic ovary syndrome

J Vrbikova, V Hainer - Obesity facts, 2009 - karger.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women
of fertile age. Obesity is encountered in 30–70% of PCOS-affected women, and its presence …