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Multielectrode arrays for functional phenoty** of neurons from induced pluripotent stem cell models of neurodevelopmental disorders
Simple Summary Multielectrode array technology allows researchers to record the
spontaneous firing activity of cultured neurons over a period of multiple weeks or months …
spontaneous firing activity of cultured neurons over a period of multiple weeks or months …
In vitro microelectrode array technology and neural recordings
In vitro microelectrode array (MEA) technology has evolved into a widely used and effective
methodology to study cultured neural networks. An MEA forms a unique electrical interface …
methodology to study cultured neural networks. An MEA forms a unique electrical interface …
Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array
The brain's extracellular matrix (ECM) is a macromolecular network composed of
glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro studies …
glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro studies …
In Vitro Studies of Neuronal Networks and Synaptic Plasticity in Invertebrates and in Mammals Using Multielectrode Arrays
Brain functions are strictly dependent on neural connections formed during development
and modified during life. The cellular and molecular mechanisms underlying …
and modified during life. The cellular and molecular mechanisms underlying …
Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures …
Due to lack of knowledge only a few industrial chemicals have been identified as
developmental neurotoxicants. Current developmental neurotoxicity (DNT) guidelines …
developmental neurotoxicants. Current developmental neurotoxicity (DNT) guidelines …
Transfer entropy reconstruction and labeling of neuronal connections from simulated calcium imaging
Neuronal dynamics are fundamentally constrained by the underlying structural network
architecture, yet much of the details of this synaptic connectivity are still unknown even in …
architecture, yet much of the details of this synaptic connectivity are still unknown even in …
Short-term memory in networks of dissociated cortical neurons
Short-term memory refers to the ability to store small amounts of stimulus-specific
information for a short period of time. It is supported by both fading and hidden memory …
information for a short period of time. It is supported by both fading and hidden memory …
Network plasticity in cortical assemblies
To investigate distributed synaptic plasticity at the cell assembly level, we used dissociated
cortical networks from embryonic rats grown on grids of 60 extracellular substrate …
cortical networks from embryonic rats grown on grids of 60 extracellular substrate …
Spatio-temporal electrical stimuli shape behavior of an embodied cortical network in a goal-directed learning task
We developed an adaptive training algorithm, whereby an in vitro neocortical network
learned to modulate its dynamics and achieve pre-determined activity states within tens of …
learned to modulate its dynamics and achieve pre-determined activity states within tens of …
A neuromorphic prosthesis to restore communication in neuronal networks
Recent advances in bioelectronics and neural engineering allowed the development of
brain machine interfaces and neuroprostheses, capable of facilitating or recovering …
brain machine interfaces and neuroprostheses, capable of facilitating or recovering …