Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced...

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HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin grafts

SD Jazayeri, PT Kuo, GR Leggatt, IH Frazer - Frontiers in immunology, 2017 - frontiersin.org
Human papillomavirus (HPV) 16 E7 (E7) protein expression in skin promotes epithelial
hyperproliferation and transformation to malignancy. Grafts of murine skin expressing E7 …
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