Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

Effective countermeasures for tendon injury remains unsatisfactory. Mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs)-based therapy via regulation of Mφ-mediated …

Plastic surgeons have used the reconstructive ladder for many decades as a standard
directory for complex trauma reconstruction with the goal of repairing body structures and …

Mesenchymal stem/stromal cells (MSCs) are multipotent cells involved in numerous
physiological events, including organogenesis, the maintenance of tissue homeostasis …

Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …

Radiotherapy (RT) mainly elicits antitumor immunity via the cGAS/STING axis for type I
interferon (IFN) production. However, dysregulation of cGAS/STING constrains radiotherapy …

Immunoengineering continues to revolutionize healthcare, generating new approaches for
treating previously intractable diseases, particularly in regard to cancer immunotherapy. In …

The tumor microenvironment is importantly shaped by various cytokines, where interleukins
(ILs) and interferons (IFNs) shape the balance of immune activity within tumor niche and …

Treating brain tumors presents enormous challenges, and there are still poor prognoses in
both adults and children. Application of novel targets and potential drugs is hindered by the …