COVID-19-associated fungal infections

M Hoenigl, D Seidel, R Sprute, C Cunha… - Nature …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Threats posed by the fungal kingdom to humans, wildlife, and agriculture

MC Fisher, SJ Gurr, CA Cuomo, DS Blehert, H **… - MBio, 2020 - Am Soc Microbiol
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …

The fungal cell wall: structure, biosynthesis, and function

NAR Gow, JP Latge, CA Munro - Microbiology spectrum, 2017 - Am Soc Microbiol
The molecular composition of the cell wall is critical for the biology and ecology of each
fungal species. Fungal walls are composed of matrix components that are embedded and …

Strategy to combat biofilms: a focus on biofilm dispersal enzymes

S Wang, Y Zhao, AP Breslawec, T Liang… - npj Biofilms and …, 2023 - nature.com
Bacterial biofilms, which consist of three-dimensional extracellular polymeric substance
(EPS), not only function as signaling networks, provide nutritional support, and facilitate …

Galactosaminogalactan activates the inflammasome to provide host protection

B Briard, T Fontaine, P Samir, DE Place, L Muszkieta… - Nature, 2020 - nature.com
Inflammasomes are important sentinels of innate immune defence that are activated in
response to diverse stimuli, including pathogen-associated molecular patterns (PAMPs) …

Polysaccharides' structures and functions in biofilm architecture of antimicrobial-resistant (AMR) pathogens

E Balducci, F Papi, DE Capialbi, L Del Bino - International journal of …, 2023 - mdpi.com
Bacteria and fungi have developed resistance to the existing therapies such as antibiotics
and antifungal drugs, and multiple mechanisms are mediating this resistance. Among these …

The interface between fungal biofilms and innate immunity

JF Kernien, BD Snarr, DC Sheppard… - Frontiers in …, 2018 - frontiersin.org
Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.
These biofilms are commonly found during infection caused by a variety of fungal …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Pathophysiological aspects of Aspergillus colonization in disease

S Gago, DW Denning, P Bowyer - Medical mycology, 2019 - academic.oup.com
Aspergillus colonization of the lower respiratory airways is common in normal people, and of
little clinical significance. However, in some patients, colonization is associated with severe …