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[HTML][HTML] Sensitive periods of substance abuse: Early risk for the transition to dependence
Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …
The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …
addiction has extended the scope of inquiry from the putative reward-related subcortical …
Psychedelic therapy in the treatment of addiction: the past, present and future
Psychedelic therapy has witnessed a resurgence in interest in the last decade from the
scientific and medical communities with evidence now building for its safety and efficacy in …
scientific and medical communities with evidence now building for its safety and efficacy in …
The neurobiology of impulsivity and substance use disorders: implications for treatment
Impulsivity is strongly associated with substance use disorders (SUDs). Our review
discusses impulsivity as an underlying vulnerability marker for SUDs, and treatment of co …
discusses impulsivity as an underlying vulnerability marker for SUDs, and treatment of co …
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …
from disruption of subcortical reward circuits. However, imaging studies in addictive …
Cerebellar networks with the cerebral cortex and basal ganglia
The dominant view of cerebellar function has been that it is exclusively concerned with
motor control and coordination. Recent findings from neuroanatomical, behavioral, and …
motor control and coordination. Recent findings from neuroanatomical, behavioral, and …
[HTML][HTML] Impulsivity, compulsivity, and top-down cognitive control
Impulsivity is the tendency to act prematurely without foresight. Behavioral and
neurobiological analysis of this construct, with evidence from both animal and human …
neurobiological analysis of this construct, with evidence from both animal and human …
[HTML][HTML] From the ventral to the dorsal striatum: devolving views of their roles in drug addiction
We revisit our hypothesis that drug addiction can be viewed as the endpoint of a series of
transitions from initial voluntarily drug use to habitual, and ultimately compulsive drug use …
transitions from initial voluntarily drug use to habitual, and ultimately compulsive drug use …
Chronic stress, drug use, and vulnerability to addiction
Stress is a well‐known risk factor in the development of addiction and in addiction relapse
vulnerability. A series of population‐based and epidemiological studies have identified …
vulnerability. A series of population‐based and epidemiological studies have identified …
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Drug addiction is increasingly viewed as the endpoint of a series of transitions from initial
drug use—when a drug is voluntarily taken because it has reinforcing, often hedonic, effects …
drug use—when a drug is voluntarily taken because it has reinforcing, often hedonic, effects …