The dawn of spatial omics
Spatial omics has been widely heralded as the new frontier in life sciences. This term
encompasses a wide range of techniques that promise to transform many areas of biology …
encompasses a wide range of techniques that promise to transform many areas of biology …
Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …
of the spatial localization of transcripts and related analyses in various applications for …
High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq
Z Xu, T Zhang, H Chen, Y Zhu, Y Lv, S Zhang… - Nature …, 2023 - nature.com
Formalin-fixed paraffin-embedded (FFPE) tissues constitute a vast and valuable patient
material bank for clinical history and follow-up data. It is still challenging to achieve single …
material bank for clinical history and follow-up data. It is still challenging to achieve single …
Deep 3D histology powered by tissue clearing, omics and AI
A Ertürk - Nature methods, 2024 - nature.com
To comprehensively understand tissue and organism physiology and pathophysiology, it is
essential to create complete three-dimensional (3D) cellular maps. These maps require …
essential to create complete three-dimensional (3D) cellular maps. These maps require …
Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics
Metasurfaces have revolutionized optical biosensing and diagnostic assays due to their
sensitivity, compactness, and label-free operation. However, metasurface applications in …
sensitivity, compactness, and label-free operation. However, metasurface applications in …
Enablers and challenges of spatial omics, a melting pot of technologies
Spatial omics has emerged as a rapidly growing and fruitful field with hundreds of
publications presenting novel methods for obtaining spatially resolved information for any …
publications presenting novel methods for obtaining spatially resolved information for any …
Multiplex protein imaging in tumour biology
Tissue imaging has become much more colourful in the past decade. Advances in both
experimental and analytical methods now make it possible to image protein markers in …
experimental and analytical methods now make it possible to image protein markers in …
Spatial transcriptomic technologies
Spatial transcriptomic technologies enable measurement of expression levels of genes
systematically throughout tissue space, deepening our understanding of cellular …
systematically throughout tissue space, deepening our understanding of cellular …
Seeing plants as never before
Imaging has long supported our ability to understand the inner life of plants, their
development, and response to a dynamic environment. While optical microscopy remains …
development, and response to a dynamic environment. While optical microscopy remains …
Barcoded multiple displacement amplification for high coverage sequencing in spatial genomics
Determining mutational landscapes in a spatial context is essential for understanding
genetically heterogeneous cell microniches. Current approaches, such as Multiple …
genetically heterogeneous cell microniches. Current approaches, such as Multiple …