[HTML][HTML] Bacteriophage lambda: Early pioneer and still relevant
SR Casjens, RW Hendrix - Virology, 2015 - Elsevier
Molecular genetic research on bacteriophage lambda carried out during its golden age from
the mid-1950s to mid-1980s was critically important in the attainment of our current …
the mid-1950s to mid-1980s was critically important in the attainment of our current …
λ recombination and recombineering
KC Murphy - EcoSal Plus, 2016 - Am Soc Microbiol
The bacteriophage λ Red homologous recombination system has been studied over the
past 50 years as a model system to define the mechanistic details of how organisms …
past 50 years as a model system to define the mechanistic details of how organisms …
[HTML][HTML] Structure and mechanism of a cyclic trinucleotide-activated bacterial endonuclease mediating bacteriophage immunity
Bacteria possess an array of defenses against foreign invaders, including a broadly
distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti …
distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti …
Subnucleosomal structures and nucleosome asymmetry across a genome
Genes are packaged into nucleosomal arrays, each nucleosome typically having two copies
of histones H2A, H2B, H3, and H4. Histones have distinct posttranslational modifications …
of histones H2A, H2B, H3, and H4. Histones have distinct posttranslational modifications …
Bacteriophage λ exonuclease and a 5′-phosphorylated DNA guide allow PAM-independent targeting of double-stranded nucleic acids
S Fu, J Li, J Chen, L Zhang, J Liu, H Liu, X Su - Nature Biotechnology, 2024 - nature.com
Sequence-specific recognition of double-stranded nucleic acids is essential for molecular
diagnostics and in situ imaging. Clustered regularly interspaced short palindromic repeats …
diagnostics and in situ imaging. Clustered regularly interspaced short palindromic repeats …
Probing and regulating the activity of cellular enzymes by using DNA tetrahedron nanostructures
Given the essential role of apurinic/apyrimidinic endonuclease (APE1) in gene repair and
cancer progression, we report a novel approach for probing and regulating cellular APE1 …
cancer progression, we report a novel approach for probing and regulating cellular APE1 …
Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS
Bacterial meningitis is well known for its rapid onset and high mortality rates, therefore rapid
detection of bacteria found in cerebral spinal fluid (CSF) and subsequent effective treatment …
detection of bacteria found in cerebral spinal fluid (CSF) and subsequent effective treatment …
Sequence, structure and functional diversity of PD-(D/E) XK phosphodiesterase superfamily
Proteins belonging to PD-(D/E) XK phosphodiesterases constitute a functionally diverse
superfamily with representatives involved in replication, restriction, DNA repair and tRNA …
superfamily with representatives involved in replication, restriction, DNA repair and tRNA …
Dna2 nuclease-helicase structure, mechanism and regulation by Rpa
C Zhou, S Pourmal, NP Pavletich - Elife, 2015 - elifesciences.org
The Dna2 nuclease-helicase maintains genomic integrity by processing DNA double-strand
breaks, Okazaki fragments and stalled replication forks. Dna2 requires ssDNA ends, and is …
breaks, Okazaki fragments and stalled replication forks. Dna2 requires ssDNA ends, and is …
The CRISPR associated protein Cas4 Is a 5′ to 3′ DNA exonuclease with an iron-sulfur cluster
J Zhang, T Kasciukovic, MF White - 2012 - journals.plos.org
The Cas4 protein is one of the core CRISPR-associated (Cas) proteins implicated in the
prokaryotic CRISPR system for antiviral defence. Cas4 is thought to play a role in the …
prokaryotic CRISPR system for antiviral defence. Cas4 is thought to play a role in the …