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Recent strategies for improving MALDI mass spectrometry imaging performance towards low molecular weight compounds
Z Sun, F Wang, Y Liu, B Deng, R Ren, Y Wang… - TrAC Trends in …, 2024 - Elsevier
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI),
traditionally used for analyzing larger molecules, faces challenges with low molecular …
traditionally used for analyzing larger molecules, faces challenges with low molecular …
Ultrahigh-mass resolution mass spectrometry imaging with an Orbitrap externally coupled to a high-performance data acquisition system
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) is a
powerful analytical tool that enables molecular sample analysis while simultaneously …
powerful analytical tool that enables molecular sample analysis while simultaneously …
Effects of sex and western diet on spatial lipidomic profiles for the hippocampus, cortex, and corpus callosum in mice using MALDI MSI
CC Shafer, J Di Lucente, UR Mendiola… - Journal of the …, 2024 - ACS Publications
Diet is inextricably linked to human health and biological functionality. Reduced cognitive
function among other health issues has been correlated with a western diet (WD) in mouse …
function among other health issues has been correlated with a western diet (WD) in mouse …
Untargeted Spatial Metabolomics and Spatial Proteomics on the Same Tissue Section
An increasing number of spatial multiomic workflows have recently been developed. Some
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
Experimental and Computational Evaluation of Lipidomic In-Source Fragmentation as a Result of Postionization with Matrix-Assisted Laser Desorption/Ionization
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
provide spatially resolved molecular information about a sample. Recently, a postionization …
provide spatially resolved molecular information about a sample. Recently, a postionization …
External Data Systems Enable Enhanced (and Sustainable) Fourier Transform Mass Spectrometry Imaging for Legacy Hybrid Linear Ion Trap–Orbitrap Platforms
FE Leach III, KO Nagornov, AN Kozhinov… - Journal of the …, 2024 - ACS Publications
Legacy Fourier transform (FT) mass spectrometers provide robust platforms for bioanalytical
mass spectrometry (MS) yet lack the most modern performance capabilities. For many …
mass spectrometry (MS) yet lack the most modern performance capabilities. For many …
Evaluation of atmospheric-plasma-source absorption mode Fourier transform Orbitrap mass spectrometry for chlorinated paraffin mixtures
C Masucci, KO Nagornov, AN Kozhinov, K Kraft… - Analytical and …, 2024 - Springer
Chlorinated paraffins (CP) are complex molecular mixtures occurring in a wide range of
isomers and homologs of environmental hazards, whose analytical complexity demand …
isomers and homologs of environmental hazards, whose analytical complexity demand …
Deep MALDI-MS Spatial 'Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy
L Gruber, S Schmidt, T Enzlein, HG Vo, JL Cairns… - bioRxiv, 2023 - biorxiv.org
In spatial 'omics, highly confident molecular identifications are indispensable for the
investigation of complex biology and for spatial biomarker discovery. However, current mass …
investigation of complex biology and for spatial biomarker discovery. However, current mass …