Photodynamic and antibiotic therapy in combination against bacterial infections: efficacy, determinants, mechanisms, and future perspectives

Y Feng, CC Tonon, S Ashraf, T Hasan - Advanced Drug Delivery Reviews, 2021 - Elsevier
Antibiotic treatment, the mainstay for the control of bacterial infections, is greatly hampered
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …

Malignant ascites in ovarian cancer: cellular, acellular, and biophysical determinants of molecular characteristics and therapy response

BP Rickard, C Conrad, AJ Sorrin, MK Ruhi, JC Reader… - Cancers, 2021 - mdpi.com
Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …

Cancer-associated fibroblast heterogeneity: a factor that cannot be ignored in immune microenvironment remodeling

PY Chen, WF Wei, HZ Wu, LS Fan… - Frontiers in immunology, 2021 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are important, highly heterogeneous components of
the tumor extracellular matrix that have different origins and express a diverse set of …

Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization—a Thomas Dougherty Award for Excellence in …

P De Silva, MA Saad, HC Thomsen, S Bano… - Journal of Porphyrins …, 2020 - World Scientific
Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …

Remediating desmoplasia with EGFR‐targeted photoactivable multi‐inhibitor liposomes doubles overall survival in pancreatic cancer

G Obaid, S Bano, H Thomsen, S Callaghan… - Advanced …, 2022 - Wiley Online Library
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …

Photodynamic therapy for pancreatic ductal adenocarcinoma

V Karimnia, FJ Slack, JP Celli - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal of
human cancers. Numerous clinical trials evaluating various combinations of chemotherapy …

Subtherapeutic photodynamic treatment facilitates tumor nanomedicine delivery and overcomes desmoplasia

M Overchuk, KM Harmatys, S Sindhwani… - Nano Letters, 2020 - ACS Publications
Limited tumor nanoparticle accumulation remains one of the main challenges in cancer
nanomedicine. Here, we demonstrate that subtherapeutic photodynamic priming (PDP) …

Overview of nanoparticle-based approaches for the combination of Photodynamic Therapy (PDT) and chemotherapy at the preclinical stage

L Menilli, C Milani, E Reddi, F Moret - Cancers, 2022 - mdpi.com
Simple Summary The present review represents the outstanding and promising recent
literature reports (2017–2022) on nanoparticle-based formulations developed for anticancer …

Pancreatic cancer (PDAC): introduction of evidence-based complementary measures into integrative clinical management

V Jentzsch, J Davis, MBA Djamgoz - Cancers, 2020 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a devastating disease that is very
hard to treat. Here, we advance and evaluate the notion that the best possible management …

[HTML][HTML] The role of photodynamic therapy in breast cancer–A review of in vitro research

M Czarnecka-Czapczyńska, D Aebisher, P Oleś… - Biomedicine & …, 2021 - Elsevier
Breast cancer is the most common cancer affecting women and the incidence of occurrence
is increasing. Currently, there are many methods of detecting and treating breast cancer …