Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Tissue engineering is approach of replacing or regeneration of biological functions of
tissues or organs by using combination of biomaterials, biomolecules and cells. Tissue …

Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a
lack of bioactive factors. Therefore, develo** bioactive materials, such as hydrogels acting …

The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Extracellular vesicles have gained wide momentum as potential therapeutics for
osteoarthritis, a highly prevalent chronic disease that still lacks an approved treatment. The …

Extracellular vesicles (EVs) are a population of small vesicles secreted by essentially all cell
types, containing a wide variety of biological macromolecules. Due to their intrinsic …

Extracellular vesicles (EV) are vesicular vesicles with phospholipid bilayer, which are
present in biological fluids and extracellular microenvironment. Extracellular vesicles serve …

Spontaneous bone regeneration encounters substantial restrictions in cases of bone
defects, demanding external intervention to improve the repair and regeneration procedure …

Mesenchymal stem cell-derived exosomes (MSC-Exos) have been utilized as medicinal
agents or as delivery vehicles in cartilage injuries and cartilage-based diseases. Given the …