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Challenges and opportunities for the next generation of cardiovascular tissue engineering
Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …
[HTML][HTML] Progress in multicellular human cardiac organoids for clinical applications
Advances in self-organizing cardiac organoids to recapitulate human cardiogenesis have
provided a powerful tool for unveiling human cardiac development, studying cardiovascular …
provided a powerful tool for unveiling human cardiac development, studying cardiovascular …
Conductive and semiconductive nanocomposite‐based hydrogels for cardiac tissue engineering
Cardiovascular disease is the leading cause of death worldwide and the most common
cause is myocardial infarction. Therefore, appropriate approaches should be used to repair …
cause is myocardial infarction. Therefore, appropriate approaches should be used to repair …
Modeling heart diseases on a chip: advantages and future opportunities
Heart disease is a significant burden on global health care systems and is a leading cause
of death each year. To improve our understanding of heart disease, high quality disease …
of death each year. To improve our understanding of heart disease, high quality disease …
Cellular and engineered organoids for cardiovascular models
An ensemble of in vitro cardiac tissue models has been developed over the past several
decades to aid our understanding of complex cardiovascular disorders using a reductionist …
decades to aid our understanding of complex cardiovascular disorders using a reductionist …
Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture
Cardiovascular diseases remain the leading cause of death worldwide; hence there is an
increasing focus on develo** physiologically relevant in vitro cardiovascular tissue …
increasing focus on develo** physiologically relevant in vitro cardiovascular tissue …
[HTML][HTML] Decellularized extracellular matrix scaffolds for cardiovascular tissue engineering: current techniques and challenges
Cardiovascular diseases are the leading cause of global mortality. Over the past two
decades, researchers have tried to provide novel solutions for end-stage heart failure to …
decades, researchers have tried to provide novel solutions for end-stage heart failure to …
Consequences of ionizing radiation exposure to the cardiovascular system
Ionizing radiation is widely used in various industrial and medical applications, resulting in
increased exposure for certain populations. Lessons from radiation accidents and …
increased exposure for certain populations. Lessons from radiation accidents and …
RNA sequencing in disease diagnosis
RNA sequencing (RNA-seq) enables the accurate measurement of multiple transcriptomic
phenotypes for modeling the impacts of disease variants. Advances in technologies …
phenotypes for modeling the impacts of disease variants. Advances in technologies …
Bioderived nanoparticles for cardiac repair
Biobased therapy represents a promising strategy for myocardial repair. However, the
limitations of using live cells, including the risk of immunogenicity of allogeneic cells and …
limitations of using live cells, including the risk of immunogenicity of allogeneic cells and …