Fluorescent molecules bound to receptors can show their location and, if binding is
reversible, can provide pharmacological information such as affinity and proximity between …

There are currently some experimental observations which point toward a new classification
of alpha-adrenoceptors, not only in terms of the recognition site, but also as initiators of …

Theoretically, new compounds with neuromuscular blocking activity might additionally
produce almost any type of unwanted pharmacological effect. However, the accumulated …

We have investigated the effects of methylenedioxymethamphetamine (MDMA,'ecstasy') on
peripheral noradrenergic neurotransmission in the rat. In rat atrial slices pre‐incubated with …

Background Patients with congenital heart disease characterized by a functional single
ventricle make up an increasing number of patients presenting for cardiac or noncardiac …

Since acetylcholine (ACh) is the 'master key'to different subtypes of nicotinic and muscarinic
receptors, and muscle relaxants (MRs) available in clinical practice are structurally related to …

BACKGROUND: Pancuronium, vecuronium, rocuronium, and mivacurium are
nondepolarizing neuromuscular blocking agents that affect the cardiovascular system with …

References CLANACHAN, AS & MCGRATH, JC (1976). Effects of ketamine on the
peripheral autonomic nervous system of the rat. Br. J. Pharmac., 58, 247-252. DOCHERTY …

The QT interval, heart rate and arterial pressure were measured during anaesthetic
induction in 186 patients without cardiovascular diseases or any preoperative drugs. The …

Rocuronium administration may cause tachycardia and an increase in cardiac index.
Pancuronium, another steroidal non-depolarizing muscle relaxant, augments release of, and …