[HTML][HTML] Is depression associated with increased oxidative stress? A systematic review and meta-analysis

CN Black, M Bot, PG Scheffer, P Cuijpers… - …, 2015 - Elsevier
Background It has been suggested that depressed persons have increased oxidative stress
and decreased anti-oxidant defences. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) and F2 …

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …

B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …

The promise of N-acetylcysteine in neuropsychiatry

M Berk, GS Malhi, LJ Gray, OM Dean - Trends in pharmacological sciences, 2013 - cell.com
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of
multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant …

An updated meta-analysis of oxidative stress markers in bipolar disorder

NC Brown, AC Andreazza, LT Young - Psychiatry research, 2014 - Elsevier
Despite its debilitating symptoms, the pathophysiology of bipolar disorder (BD) remains
unclear. One consistently compelling finding, however, has been the presence of oxidative …

Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

AC Andreazza, L Shao, JF Wang… - Archives of general …, 2010 - jamanetwork.com
Context Accumulating evidence suggests that mitochondrial dysfunction and oxidative stress
contribute to the pathogenesis of bipolar disorder and schizophrenia. It remains unclear …

Oxidative stress markers in bipolar disorder: a meta-analysis

AC Andreazza, M Kauer-Sant'Anna, BN Frey… - Journal of affective …, 2008 - Elsevier
BACKGROUND: Oxidative stress is thought to mediate neuropathological processes of a
number of neuropsychiatric disorders and recent data suggest that oxidative stress may be …

Oxidative stress in anxiety and comorbid disorders

I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

Allostatic load in bipolar disorder: implications for pathophysiology and treatment

F Kapczinski, E Vieta, AC Andreazza, BN Frey… - Neuroscience & …, 2008 - Elsevier
Current literature on the effects of chronic stress in general health converges to the concept
of allostatic load (AL). AL is the bodily 'wear and tear'that emerges with sustained allostatic …