Examining the healthy human microbiome concept

R Joos, K Boucher, A Lavelle, M Arumugam… - Nature Reviews …, 2024 - nature.com
Human microbiomes are essential to health throughout the lifespan and are increasingly
recognized and studied for their roles in metabolic, immunological and neurological …

The role of the intestine in the development of hyperuricemia

H Yin, N Liu, J Chen - Frontiers in immunology, 2022 - frontiersin.org
Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in
the joints. Hyperuricemia is the fundamental factor of gout. The onset of hyperuricemia is …

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

X Liu, X Tong, Y Zou, X Lin, H Zhao, L Tian, Z Jie… - Nature …, 2022 - nature.com
The gut microbiome has been implicated in a variety of physiological states, but controversy
over causality remains unresolved. Here, we performed bidirectional Mendelian …

Artificial intelligence and personalized diagnostics in periodontology: A narrative review

V Pitchika, M Büttner, F Schwendicke - Periodontology 2000, 2024 - Wiley Online Library
Periodontal diseases pose a significant global health burden, requiring early detection and
personalized treatment approaches. Traditional diagnostic approaches in periodontology …

Metagenomics: An effective approach for exploring microbial diversity and functions

NN Nam, HDK Do, KT Loan Trinh, NY Lee - Foods, 2023 - mdpi.com
Various fields have been identified in the “omics” era, such as genomics, proteomics,
transcriptomics, metabolomics, phenomics, and metagenomics. Among these …

Identifying keystone species in microbial communities using deep learning

XW Wang, Z Sun, H Jia, S Michel-Mata… - Nature Ecology & …, 2024 - nature.com
Previous studies suggested that microbial communities can harbour keystone species
whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an …

Revealing the association between East Asian oral microbiome and colorectal cancer through Mendelian randomization and multi-omics analysis

Y Gu, L Jiang, M Shui, H Luo, X Zhou… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Colorectal cancer (CRC) poses a global health threat, with the oral microbiome
increasingly implicated in its pathogenesis. This study leverages Mendelian Randomization …

Oral microbiota and metabolites: key players in oral health and disorder, and microbiota-based therapies

N Bostanghadiri, M Kouhzad, E Taki, Z Elahi… - Frontiers in …, 2024 - frontiersin.org
The review aimed to investigate the diversity of oral microbiota and its influencing factors, as
well as the association of oral microbiota with oral health and the possible effects of …

Sex differences in the oral microbiome, host traits, and their causal relationships

X Liu, X Tong, Z Jie, J Zhu, L Tian, Q Sun, Y Ju, L Zou… - IScience, 2023 - cell.com
The oral microbiome has been implicated in a growing number of diseases; however,
determinants of the oral microbiome and their roles remain elusive. Here, we investigated …

The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights

Y Li, M Zhu, Y Liu, B Luo, J Cui, L Huang… - Frontiers in …, 2022 - frontiersin.org
There is mounting evidence demonstrating that oral dysbiosis causes periodontal disease
and promotes the development of cardiovascular disease. The advancement of omics …