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Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021
Q Wu, W Qian, X Sun, S Jiang - Journal of hematology & oncology, 2022 - Springer
Abstract The United States Food and Drug Administration (US FDA) has always been a
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …
Mesoporous silica nanoparticles for drug delivery
In recent years, nanomedicine has emerged at the forefront of nanotechnology, generating
great expectations in the biomedical field. Researchers are develo** novel nanoparticles …
great expectations in the biomedical field. Researchers are develo** novel nanoparticles …
Exploiting the folate receptor α in oncology
Folate receptor α (FRα) came into focus as an anticancer target many decades after the
successful development of drugs targeting intracellular folate metabolism, such as …
successful development of drugs targeting intracellular folate metabolism, such as …
Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems
Conventional chemotherapy lacking target selectivity often leads to severe side effects,
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …
Recent advances in active targeting of nanomaterials for anticancer drug delivery
One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
[HTML][HTML] Antioxidant, anti-obesity, nutritional and other beneficial effects of different chili pepper: A review
Fruits and vegetables are important components of a healthy diet. They are rich sources of
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …
Advances in targeting the folate receptor in the treatment/imaging of cancers
The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression
on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
Nanoparticle-based drug delivery systems targeting cancer cell surfaces
L Hong, W Li, Y Li, S Yin - RSC advances, 2023 - pubs.rsc.org
Traditional cancer chemotherapy easily produces serious toxic and side effects due to the
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …
Ligand-targeted drug delivery
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …