Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

Autophagy is a process that targets various intracellular elements for degradation.
Autophagy can be non-selective—associated with the indiscriminate engulfment of cytosolic …

Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …

Mitochondria play key roles in bioenergetics, metabolism, and signaling; therefore, stable
mitochondrial function is essential for cell survival, particularly in energy-intensive neuronal …

Degradation of mitochondria via a selective form of autophagy, named mitophagy, is a
fundamental mechanism conserved from yeast to humans that regulates mitochondrial …

As a central hub for cellular metabolism and intracellular signaling, the mitochondrion is a
pivotal organelle, dysfunction of which has been linked to several human diseases including …

Selective autophagy is the lysosomal degradation of specific intracellular components
sequestered into autophagosomes, late endosomes, or lysosomes through the activity of …

When cells are stressed, DNA from energy-producing mitochondria can leak out and drive
inflammatory immune responses if not cleared. Cells employ a quality control system called …

Ferroptosis is an iron-driven cell death modality characterized by iron accumulation and
excessive lipid peroxidation. Ferroptosis is closely related to mitochondrial function, as …