NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

MicroRNAs (miRNAs) are single-stranded, endogenous non-coding small RNAs, ranging
from 18 to 25 nucleotides in length. Growing evidence suggests that miRNAs are essential …

A substantial proportion of patients with acute graft-versus-host disease (aGVHD) respond to
cell therapy with culture-expanded human bone marrow mesenchymal stromal/stem cells …

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Rheumatoid arthritis (RA) is a polygenic disease characterized by autoimmunity and
systemic inflammation with progressive impairment of joints that results in lifelong disability …

MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

Abstract miRNA-21 is among the most abundant and highly conserved microRNAs
(miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory …

Circulating exosome holds great potentials as biomarker for diagnosis and prognosis of
human cancers. Previously, we have applied small RNA sequencing to identify aberrantly …

Autoimmune diseases occur when the immune system attacks and destroys the organs and
tissues of its own host. Autoimmunity is the third most common type of disease in the United …