The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?
An important challenge during the COVID-19 pandemic has been to understand
asymptomatic disease and the extent to which this may be a source of transmission. As …
asymptomatic disease and the extent to which this may be a source of transmission. As …
COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask …
Scientists across disciplines, policymakers, and journalists have voiced frustration at the
unprecedented polarization and misinformation around coronavirus disease 2019 (COVID …
unprecedented polarization and misinformation around coronavirus disease 2019 (COVID …
[HTML][HTML] Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3 …
F Ader, M Bouscambert-Duchamp, M Hites… - The Lancet infectious …, 2022 - thelancet.com
Background The antiviral efficacy of remdesivir against SARS-CoV-2 is still controversial.
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
Abstract The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues
L Zhang, A Richards, MI Barrasa… - Proceedings of the …, 2021 - National Acad Sciences
Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
RNA and recurrence of PCR-positive tests have been widely reported in patients after …
RNA and recurrence of PCR-positive tests have been widely reported in patients after …
Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19
The upper respiratory tract is compromised in the early period of COVID-19, but SARS-CoV-
2 tropism at the cellular level is not fully defined. Unlike recent single-cell RNA-Seq analyses …
2 tropism at the cellular level is not fully defined. Unlike recent single-cell RNA-Seq analyses …
Review of current COVID-19 diagnostics and opportunities for further development
Diagnostic testing plays a critical role in addressing the coronavirus disease 2019 (COVID-
19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV …
19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV …
Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time
Background: Information on SARS-CoV-2 in representative community surveillance is
limited, particularly cycle threshold (Ct) values (a proxy for viral load). Methods: We included …
limited, particularly cycle threshold (Ct) values (a proxy for viral load). Methods: We included …
Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device
Portable assays for the rapid identification of lineages of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) are needed to aid large-scale efforts in monitoring the …
coronavirus 2 (SARS-CoV-2) are needed to aid large-scale efforts in monitoring the …
Toward a next-generation diagnostic tool: A review on emerging isothermal nucleic acid amplification techniques for the detection of SARS-CoV-2 and other infectious …
As the COVID-19 pandemic continues to affect human health across the globe rapid, simple,
point-of-care (POC) diagnosis of infectious viruses such as SARS-CoV-2 remains …
point-of-care (POC) diagnosis of infectious viruses such as SARS-CoV-2 remains …