Abstract The recently proposed Research Domain Criteria (RDoC) system defines
psychopathologies as phenomena of multilevel neurobiological existence and assigns them …

Over the past 15 years, computational models have had a considerable impact on basal-
ganglia research. Most of these models implement multiple distinct basal-ganglia pathways …

Instrumental behavior depends on both goal-directed and habitual mechanisms of choice.
Normative views cast these mechanisms in terms of model-free and model-based methods …

The investigation of the human intelligence, cognitive systems and functional complexity of
human brain is significantly facilitated by high-performance computational platforms. In this …

Mindfulness and mindful meditation have become widely used approaches in clinical
psychology. The growing use of these techniques has increased demand in research …

E3 ubiquitin ligase (UBE3A) levels in the brain need to be tightly regulated, as loss of
functional UBE3A protein is responsible for the severe neurodevelopmental disorder …

Many computational models of the basal ganglia (BG) have been proposed over the past
twenty-five years. While computational neuroscience models have focused on closely …

To make an optimal decision we need to weigh all the available options, compare them with
the current goal, and choose the most rewarding one. Depending on the situation an optimal …

Basal ganglia (BG) are a widely recognized neural basis for action selection, but its decision-
making mechanism is still a difficult problem for researchers. Therefore, we constructed a …

Spatially segregated cortico-basal ganglia networks have been proposed for the control of
goal-directed and habitual behavior. In Parkinson's disease, selective loss of dopaminergic …