Bone turnover markers: Emerging tool in the management of osteoporosis
Bone is a dynamic tissue which undergoes constant remodeling throughout the life span.
Bone turnover is balanced with coupling of bone formation and resorption at various rates …
Bone turnover is balanced with coupling of bone formation and resorption at various rates …
Bone turnover markers in the diagnosis and monitoring of metabolic bone disease
MB Greenblatt, JN Tsai, MN Wein - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Disorders of bone metabolism, most notably osteoporosis, are highly
prevalent and predispose to fractures, causing high patient morbidity and mortality …
prevalent and predispose to fractures, causing high patient morbidity and mortality …
Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
SC Manolagas - Endocrine reviews, 2000 - academic.oup.com
The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins
OBJECTIVES: Contemporary adhesives lose their bond strength to dentin regardless of the
bonding system used. This loss relates to the hydrolysis of collagen matrix of the hybrid …
bonding system used. This loss relates to the hydrolysis of collagen matrix of the hybrid …
In vitro Models of Bone Remodelling and Associated Disorders
Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …
Current developments in salivary diagnostics
Salivary diagnostics is an emerging field that has progressed through several important
developments in the past decade, including the publication of the human salivary proteome …
developments in the past decade, including the publication of the human salivary proteome …
Podoplanin-expressing macrophages promote lymphangiogenesis and lymphoinvasion in breast cancer
P Bieniasz-Krzywiec, R Martín-Pérez, M Ehling… - Cell metabolism, 2019 - cell.com
Among mammary tumor-infiltrating immune cells, the highest expression of podoplanin
(PDPN) is found in a subset of tumor-associated macrophages (TAMs). We hereby …
(PDPN) is found in a subset of tumor-associated macrophages (TAMs). We hereby …
Dentin adhesion and MMPs: a comprehensive review
This review examines the fundamental processes responsible for the aging mechanisms
involved in the degradation of resin‐bonded interfaces, as well as some potential …
involved in the degradation of resin‐bonded interfaces, as well as some potential …
Bone turnover markers: use in osteoporosis
K Naylor, R Eastell - Nature Reviews Rheumatology, 2012 - nature.com
Biochemical markers of bone turnover (bone turnover markers, BTMs) can be used to study
changes in bone remodelling in osteoporosis. Investigators and clinicians should be aware …
changes in bone remodelling in osteoporosis. Investigators and clinicians should be aware …
Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more …
Increased attention is paid to the structural components of tissues. These components are
mostly collagens and various proteoglycans. Emerging evidence suggests that altered …
mostly collagens and various proteoglycans. Emerging evidence suggests that altered …