Bone turnover markers: Emerging tool in the management of osteoporosis

S Shetty, N Kapoor, JD Bondu… - Indian journal of …, 2016 - journals.lww.com
Bone is a dynamic tissue which undergoes constant remodeling throughout the life span.
Bone turnover is balanced with coupling of bone formation and resorption at various rates …

Bone turnover markers in the diagnosis and monitoring of metabolic bone disease

MB Greenblatt, JN Tsai, MN Wein - Clinical chemistry, 2017 - academic.oup.com
BACKGROUND Disorders of bone metabolism, most notably osteoporosis, are highly
prevalent and predispose to fractures, causing high patient morbidity and mortality …

Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis

SC Manolagas - Endocrine reviews, 2000 - academic.oup.com
The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …

Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins

L Tjäderhane, FD Nascimento, L Breschi, A Mazzoni… - Dental Materials, 2013 - Elsevier
OBJECTIVES: Contemporary adhesives lose their bond strength to dentin regardless of the
bonding system used. This loss relates to the hydrolysis of collagen matrix of the hybrid …

In vitro Models of Bone Remodelling and Associated Disorders

R Owen, GC Reilly - Frontiers in bioengineering and biotechnology, 2018 - frontiersin.org
Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …

Current developments in salivary diagnostics

CS Miller, JD Foley, AL Bailey, CL Campell… - Biomarkers in …, 2010 - Taylor & Francis
Salivary diagnostics is an emerging field that has progressed through several important
developments in the past decade, including the publication of the human salivary proteome …

Podoplanin-expressing macrophages promote lymphangiogenesis and lymphoinvasion in breast cancer

P Bieniasz-Krzywiec, R Martín-Pérez, M Ehling… - Cell metabolism, 2019 - cell.com
Among mammary tumor-infiltrating immune cells, the highest expression of podoplanin
(PDPN) is found in a subset of tumor-associated macrophages (TAMs). We hereby …

Dentin adhesion and MMPs: a comprehensive review

J Perdigão, A Reis, AD Loguercio - Journal of esthetic and …, 2013 - Wiley Online Library
This review examines the fundamental processes responsible for the aging mechanisms
involved in the degradation of resin‐bonded interfaces, as well as some potential …

Bone turnover markers: use in osteoporosis

K Naylor, R Eastell - Nature Reviews Rheumatology, 2012 - nature.com
Biochemical markers of bone turnover (bone turnover markers, BTMs) can be used to study
changes in bone remodelling in osteoporosis. Investigators and clinicians should be aware …

Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more …

MA Karsdal, MJ Nielsen, JM Sand… - Assay and drug …, 2013 - liebertpub.com
Increased attention is paid to the structural components of tissues. These components are
mostly collagens and various proteoglycans. Emerging evidence suggests that altered …