Non-coding RNA in cancer drug resistance: underlying mechanisms and clinical applications

X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …

[HTML][HTML] Exosomal non-coding RNAs: new insights into the biology of hepatocellular carcinoma

Q Zhang, H Li, Y Liu, J Li, C Wu, H Tang - Current Oncology, 2022 - mdpi.com
Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest
extracellular vesicles released by cells. They deliver different cargoes, including proteins …

Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies

C Bajo-Santos, A Brokāne, P Zayakin… - Frontiers in molecular …, 2023 - frontiersin.org
Introduction: Extracellular vesicles (EVs) have emerged as a very attractive source of cancer-
derived RNA biomarkers for the early detection, prognosis and monitoring of various …

Long non-coding RNAs (lncRNAs) as regulators of the PI3K/AKT/mTOR pathway in gastric carcinoma

I Riquelme, P Pérez-Moreno, B Mora-Lagos… - International Journal of …, 2023 - mdpi.com
Gastric cancer (GC) represents~ 10% of the global cancer-related deaths, increasingly
affecting the younger population in active stages of life. The high mortality of GC is due to …

[HTML][HTML] Noncoding RNAs emerging as drugs or drug targets: their chemical modification, bio-conjugation and intracellular regulation

J Wang, T Tian, X Li, Y Zhang - Molecules, 2022 - mdpi.com
With the increasing understanding of various disease-related noncoding RNAs, ncRNAs are
emerging as novel drugs and drug targets. Nucleic acid drugs based on different types of …

[HTML][HTML] Recent trends and advancements in the diagnosis and management of gastric cancer

E Haque, A Esmail, I Muhsen, H Salah, M Abdelrahim - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer is the fifth most common tumor worldwide. In the past
couple of decades, there have been many advancements toward earlier detection and better …

[HTML][HTML] RNA-based liquid biopsy in head and neck cancer

J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Epigenetic regulation of inflammation: The metabolomics connection

S Rath, YM Hawsawi, F Alzahrani, MI Khan - Seminars in Cell & …, 2024 - Elsevier
Epigenetic factors are considered the regulator of complex machinery behind inflammatory
disorders and significantly contributed to the expression of inflammation-associated genes …

Modulation of faecal miRNAs highlights the preventive effects of a Mediterranean low-inflammatory dietary intervention

O Illescas, G Ferrero, A Belfiore, B Pardini, S Tarallo… - Clinical Nutrition, 2024 - Elsevier
Background Dietary interventions have been proposed as therapeutic approaches for
several diseases, including cancer. A low-inflammatory Mediterranean dietary intervention …

Advances in RNA interference for plant functional genomics: unveiling traits, mechanisms, and future directions

D Chaudhary, AS Jeena, Rohit, S Gaur, R Raj… - Applied Biochemistry …, 2024 - Springer
RNA interference (RNAi) is a conserved molecular mechanism that plays a critical role in
post-transcriptional gene silencing across diverse organisms. This review delves into the …