Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

During the past decade, major advances have been made in the accurate diagnosis of
severe cutaneous adverse reactions (SCARs) to drugs, management of their manifestations …

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

When drug reactions resembling allergy occur, they are called drug hypersensitivity
reactions (DHR s) before showing the evidence of either drug‐specific antibodies or T cells …

As precision medicine becomes increasingly relevant in healthcare, the field of
pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading …

Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an
uncommon drug adverse reaction that can develop to conditions spanning from …

Drug hypersensitivity reactions (DHR) are based on distinct mechanisms and are clinically
heterogeneous. Taking into account that also off‐target activities of drugs may lead to …

Drug-induced liver injury (DILI) can broadly be divided into predictable and dose dependent
such as acetaminophen (APAP) and unpredictable or idiosyncratic DILI (IDILI). Liver injury …

Dermatology, edited by world authorities Jean L. Bolognia, MD, Joseph L. Jorizzo, MD, and
Julie V. Schaffer, MD, is an all-encompassing medical reference book that puts the latest …

Controversies exist with regard to in vivo approaches to delayed immunologically mediated
adverse drug reactions, such as exanthem (maculopapular eruption), drug reaction with …