Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

Since the discovery of X-ray diffraction and its potential to elucidate crystal symmetry,
powder X-ray diffraction has found diverse applications in the field of pharmaceutical …

" Polymorphism in the Pharmaceutical Industry-Solid Form and Drug Development"
highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus …

For poorly water soluble drugs, the amorphous state provides an avenue to enhance oral
bioavailability. The preparation method, in addition to sample history, can dictate the nature …

Tableting by direct compression (DC) is one of the simplest and most cost-effective drug
manufacturing approaches. However, most active pharmaceutical ingredients (APIs) and …

Low aqueous solubility of active pharmaceutical ingredients (APIs) is one of the most
important challenges facing drug development researchers today [1, 2]. With the …

In recent years, there is a growing interest in improving the physicochemical stability of
amorphous pharmaceutical solids due to their very promising applications to manufacture …

Solid dosage forms such as tablets are extensively used in drug administration for their
simplicity and large-scale manufacturing capabilities. High-resolution X-ray tomography is …

Tablets of amorphous indomethacin were compressed at 10, 25, 50, or 100 MPa using
either an unlubricated or a lubricated die and stored individually at 35° C in sealed Mylar …

Novel multifunctional excipients were prepared by coprocessing tapioca starch with
mannitol using two methods viz; co-grinding and co-fusion. The flow, packing and …