Targeting the tumour vasculature: from vessel destruction to promotion

S Guelfi, K Hodivala-Dilke, G Bergers - Nature Reviews Cancer, 2024 - nature.com
As angiogenesis was recognized as a core hallmark of cancer growth and survival, several
strategies have been implemented to target the tumour vasculature. Yet to date, attempts …

Understanding tumour endothelial cell heterogeneity and function from single-cell omics

Q Zeng, M Mousa, AS Nadukkandy, L Franssens… - Nature Reviews …, 2023 - nature.com
Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …

Targeting the lung tumor microenvironment by phytochemicals and their nanoformulations

SO Rab, FMA Altalbawy, M Chandra, IA Ariffin… - … -Research and Practice, 2024 - Elsevier
Lung malignancies are among the most prevalent and foremost causes of tumor-related
deaths. Despite significant advancements in the understanding and management of lung …
Q Liu, P Wu, J Lei, P Bai, P Zhong, M Yang… - International Journal of …, 2024 - Elsevier
Over the past few decades, research on cancer immunotherapy has firmly established
immune cells as key players in effective cancer treatment. Peptide vaccines directly targeting …

Key role of astrocytes in postnatal brain and retinal angiogenesis

M Puebla, PJ Tapia, H Espinoza - International Journal of Molecular …, 2022 - mdpi.com
Angiogenesis is a key process in various physiological and pathological conditions in the
nervous system and in the retina during postnatal life. Although an increasing number of …