Pyroptosis: a new regulating mechanism in cardiovascular disease

N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and
apoptosis, pyroptosis has unique characteristics in morphology and mechanism …

The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction

SDF Stuart, NM De Jesus, ML Lindsey… - Journal of molecular and …, 2016 - Elsevier
Optimal healing of damaged tissue following myocardial infarction (MI) requires a
coordinated cellular response that can be divided into three phases: inflammatory …

A review of interleukin-1 in heart disease: where do we stand today?

Y Szekely, Y Arbel - Cardiology and therapy, 2018 - Springer
Cardiovascular diseases are the leading cause of death worldwide. Research in the last two
decades has emphasized the inflammatory process as a key component in the …

Electroimmunology and cardiac arrhythmia

J Grune, M Yamazoe, M Nahrendorf - Nature reviews cardiology, 2021 - nature.com
Conduction disorders and arrhythmias remain difficult to treat and are increasingly prevalent
owing to the increasing age and body mass of the general population, because both are risk …

Regulatory mechanisms of the NLRP3 inflammasome, a novel immune-inflammatory marker in cardiovascular diseases

N An, Y Gao, Z Si, H Zhang, L Wang, C Tian… - Frontiers in …, 2019 - frontiersin.org
The nod-like receptor family pyrin domain containing 3 (NLRP3) is currently the most widely
studied inflammasome and has become a hot topic of recent research. As a macromolecular …

COVID-19 mRNA vaccines: the molecular basis of some adverse events

G Giannotta, A Murrone, N Giannotta - Vaccines, 2023 - mdpi.com
Each injection of any known vaccine results in a strong expression of pro-inflammatory
cytokines. This is the result of the innate immune system activation, without which no …

Nonmyocytes as electrophysiological contributors to cardiac excitation and conduction

A Simon-Chica, EM Wülfers… - American Journal of …, 2023 - journals.physiology.org
Although cardiac action potential (AP) generation and propagation have traditionally been
attributed exclusively to cardiomyocytes (CM), other cell types in the heart are also capable …

Comprehensive mechanism, novel markers and multidisciplinary treatment of severe acute pancreatitis-associated cardiac injury–a narrative review

YL Luo, ZX Li, P Ge, HY Guo, L Li… - Journal of …, 2021 - Taylor & Francis
Acute pancreatitis (AP) is one of the common acute abdominal inflammatory diseases in
clinic with acute onset and rapid progress. About 20% of the patients will eventually develop …

Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1. 2 expression

G Xue, D Li, Z Wang, Y Liu, J Yang, C Li, X Li… - Acta Pharmacologica …, 2021 - nature.com
Abstract Interleukin-17 (IL-17), also called IL-17A, is an important regulator of cardiac
diseases, but its role in calcium-related cardiac dysfunction remains to be explored. Thus …

Potential pathophysiological mechanisms underlying multiple organ dysfunction in cytokine release syndrome

P Chen, Y Tang, W He, R Yang, Z Lan… - Mediators of …, 2022 - Wiley Online Library
In recent decades, many serious respiratory infections have broken out all over the world,
including SARS‐CoV, MERS, and COVID‐19. They are characterized by strong infectivity …