[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: Applications, advantages and disadvantages

P Ghasemiyeh… - Research in …, 2018 - journals.lww.com
During the recent years, more attentions have been focused on lipid base drug delivery
system to overcome some limitations of conventional formulations. Among these delivery …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

Aerosolizable siRNA-encapsulated solid lipid nanoparticles prepared by thin-film freeze-drying for potential pulmonary delivery

JL Wang, MS Hanafy, H Xu, J Leal, Y Zhai… - International Journal of …, 2021 - Elsevier
Lipid nanoparticles are increasingly used for drug and gene delivery, including the delivery
of small interfering RNA (siRNA). Pulmonary delivery of drug molecules carried by lipid …

Evaluation of sonication on stability-indicating properties of optimized pilocarpine hydrochloride-loaded niosomes in ocular drug delivery

K Owodeha-Ashaka, MO Ilomuanya, A Iyire - Progress in biomaterials, 2021 - Springer
Niosomes are increasingly explored for enhancing drug penetration and retention in ocular
tissues for both posterior and anterior eye delivery. They have been employed in …

Applications of nanomaterials in leishmaniasis: a focus on recent advances and challenges

K Saleem, Z Khursheed, C Hano, I Anjum, S Anjum - Nanomaterials, 2019 - mdpi.com
Leishmaniasis is a widely distributed protozoan vector-born disease affecting almost 350
million people. Initially, chemotherapeutic drugs were employed for leishmania treatment but …

Development and preclinical evaluation of microneedle-assisted resveratrol loaded nanostructured lipid carriers for localized delivery to breast cancer therapy

S Gadag, R Narayan, AS Nayak, DC Ardila… - International journal of …, 2021 - Elsevier
Resveratrol (RVT) is one of the potent anticancer phytochemicals which has shown
promising potential for breast cancer therapy. However, its short half-life and low …

In vitro and in vivo evaluation of therapy targeting epithelial-cell adhesion-molecule aptamers for non-small cell lung cancer

M Alibolandi, M Ramezani, K Abnous, F Sadeghi… - Journal of Controlled …, 2015 - Elsevier
Targeted, disease-specific delivery of therapeutic nanoparticles shows wonderful promise
for transmitting highly cytotoxic anti-cancer agents. Using the reaction of non-small cell lung …

Systematic development and characterization of novel, high drug-loaded, photostable, curcumin solid lipid nanoparticle hydrogel for wound healing

SK Sandhu, S Kumar, J Raut, M Singh, S Kaur… - Antioxidants, 2021 - mdpi.com
The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid
nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure …

The effects of solid and liquid lipids on the physicochemical properties of nanostructured lipid carriers

M Apostolou, S Assi, AA Fatokun, I Khan - Journal of pharmaceutical …, 2021 - Elsevier
The aim of this work was to identify from a review of current literature the effects of lipids
used in the development of Nanostructured Lipid Carriers (NLCs) on the physicochemical …